Reported food-related symptoms and food allergen sensitization in a selected adult population in Hyderabad, India: A hospital-based survey.

Autor:	Dadha P; Center for Food Allergy & Asthma Research (CFAAR), Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill., Nimmagadda S; Center for Food Allergy & Asthma Research (CFAAR), Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.; Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Ill., Venter C; Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Ill.; Department of Pediatrics-Allergy/Immunology, CFAAR, Chicago, Ill., Gupta R; Center for Food Allergy & Asthma Research (CFAAR), Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.; Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Ill., Kumar PU; Division of Pathology & Microbiology, Indian Council of Medical Research-National Institute of Nutrition, Ministry of Health and Family Welfare, Government of India, Hyderabad, Telangana, India., Warren CM; Center for Food Allergy & Asthma Research (CFAAR), Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Jazyk:	angličtina
Zdroj:	The journal of allergy and clinical immunology. Global [J Allergy Clin Immunol Glob] 2023 Dec 23; Vol. 3 (2), pp. 100204. Date of Electronic Publication: 2023 Dec 23 (Print Publication: 2024).
DOI:	10.1016/j.jacig.2023.100204
Abstrakt:	Background: Research on reported food-related triggers of atopic disease in South Asian adults is lacking despite the region's large population and the global significance of allergic diseases. Objectives: The study aimed to identify prevalent local food items and assess allergic sensitization rates to potential trigger foods for atopic diseases via skin prick and specific IgE testing. Methods: The study began with a pilot survey of 100 subjects recruited from 4 hospitals in Hyderabad, India, focusing on foods perceived to relate to asthma, allergic rhinitis, atopic dermatitis, urticaria, and gastrointestinal allergic symptoms. A subsequent main study evaluated 2010 participants, 1754 of whom were diagnosed with an aforementioned atopic disease and who reported allergic symptoms related to any of 77 foods identified in the pilot study. Ultimately 1622 patients who consented to skin prick and specific IgE testing and who reported at least 1 food item triggering allergic diseases were included in the final analysis. Results: Among 1622 patients (average age, 42.6 ± 12.9 years; 55.5% male), asthma was the most commonly diagnosed atopic disease (26.4%), with itching and rash being frequently reported symptoms (22.7%). Notably, 94.9% of patients had total serum IgE > 144 kU/L. Chickpea, cabbage, eggplant, walnut, cumin, and betel leaf were the most commonly reported trigger foods. Conclusion: In this sample of South Indian adults diagnosed with allergic disease, reported food triggers were most commonly local dietary staples, while reported reactions to priority allergens like peanut and sesame were conspicuously absent. Observed concordance between patient-reported food triggers and sensitization to reported food triggers was low, highlighting the need for improved clinical evaluation of suspected triggers. (© 2023 The Author(s).)
Databáze:	MEDLINE
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