[Acute cholangitis due to Candida glabrata and Klebsiella pneumoniae].

Autor: Durán MV; Unidad de Infectología, Sanatorio Dr. Julio Méndez, Buenos Aires, Argentina. E-mail: dravanesaduran@gmail.com., Viceconte RV; Unidad de Infectología, Sanatorio Dr. Julio Méndez, Buenos Aires, Argentina., La Torre A; Servicio de Cirugía General, Sanatorio Dr. Julio Méndez, Buenos Aires, Argentina.
Jazyk: Spanish; Castilian
Zdroj: Medicina [Medicina (B Aires)] 2024; Vol. 84 (1), pp. 168-170.
Abstrakt: Acute cholangitis is a bile duct infection associated with bile duct obstruction. Bile culture is positive in most cases, and the most frequent etiological agent is Escherichia coli. Candida sp acute cholangitis is a rare finding, which is more common in patients with immunosuppression, use of corticosteroids, prolonged antibiotic treatment or surgical procedures of the bile duct. We present the case of a 67-year-old woman with none of the above-mentioned history who consulted for fever, abdominal pain and jaundice. MRI of the abdomen revealed a lithiasic image in the common bile duct with dilation. It required endoscopic drainage of the biliary tract. Direct microscopic examination of the bile fluid revealed gram-negative bacilli and yeast, and in the culture of bile fluid Klebsiella pneumoniae producing extended spectrum beta-lactamase (ESBL) and Candida glabrata were isolated. The patient completed the antibiotic treatment with piperacillin tazobactam and anidulafungin with good evolution. Bile duct infection by association of Gram-negative bacilli and Candida sp is a rare entity, more in patients without underlying diseases.
Databáze: MEDLINE