Optic Disc Edema Is an Under-Recognized Feature of Birdshot Chorioretinitis.

Autor: Sabapathypillai S; Washington University in St. Louis School of Medicine (SS, GVS, LMH), St. Louis, Missouri; Indiana University School of Medicine (VJM, RSM), Indianapolis, Indiana; John A. Moran Eye Center (A. Shakoor, AV), University of Utah, Salt Lake City, Utah; Sue Anschutz-Rogers Eye Center (AGP), University of Colorado School of Medicine, Denver, Colorado; Wilmer Eye Institute (JET), Johns Hopkins University School of Medicine, Baltimore, Maryland; Northwestern University Feinberg School of Medicine (DAG), Chicago, Illinois; CT Uveitis Foundation (PAG), West Hartford, ConnecticutManhattan Eye, Ear and Throat Hospital (NG), New York, New York; Hospital Universario Austral (A. Schlaen), Austral University, Buenos Aires, Argentina; Tennessee Retina (AT), Nashville, Tennessee; Rush University/Illinois Retina Associates (PTM, VR), Chicago, Illinois; Cole Eye Institute (PL), Cleveland Clinic, Cleveland, Ohio; University of Puerto Rico (ALO), San Juan, Puerto Rico; Associated Vitreoretinal and Uveitis Consultants (RSM), Carmel, Indiana; SightMD (GC), Yonkers, New York; Fundacion Jimenez Diaz University Hospital (EC), Madrid, Spain; and Mayo Clinic (WMS), Rochester, Minnesota., Miller VJ, Shakoor A, Palestine AG, Thorne JE, Goldstein DA, Gaudio PA, Goldberg N, Vitale A, Schlaen A, Thomas A, Merrill PT, Raiji V, Lin P, Oliver AL, Moorthy RS, Chandra G, Carreno E, Smith WM, Van Stavern G, Hassman LM
Jazyk: angličtina
Zdroj: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society [J Neuroophthalmol] 2024 Jan 25. Date of Electronic Publication: 2024 Jan 25.
DOI: 10.1097/WNO.0000000000002085
Abstrakt: Background: Optic disc edema is a feature of many ophthalmic and neurologic conditions. It remains an underappreciated feature of birdshot chorioretinitis (BSCR), leading to delay in diagnosis and treatment. The purpose of our study was to identify clinical features that are concomitant with optic disc edema and suggest a diagnosis of BSCR.
Methods: Retrospective multicenter case series of 29 patients who were referred to a neuro-ophthalmologist or uveitis specialist for evaluation of disc edema and were ultimately diagnosed with BSCR.
Results: Fifty-four eyes of 30 patients, from the practices of 15 uveitis specialists, met the eligibility criteria. In addition to disc edema, concomitant features in all patients included vitritis, chorioretinal lesions, and retinal vasculitis. Visual recovery to 20/40 or better occurred in 26 of 29 patients. Visual acuity remained 20/100 or worse in 2 patients previously diagnosed with idiopathic intracranial hypertension, 1 patient previously diagnosed with optic neuritis, and 1 patient for whom treatment was delayed for years, leading to optic disc atrophy.
Conclusions: Optic disc edema is a presenting feature in some cases of BSCR. A diagnosis of BSCR should be considered when disc edema occurs with vitritis, chorioretinal inflammation, and retinal vasculitis. Patients should be referred to a uveitis specialist for treatment.
Competing Interests: The authors report no conflicts of interest.
(Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the North American Neuro-Opthalmology Society.)
Databáze: MEDLINE