Effects of reduced sedentary time on resting, exercise and post-exercise blood pressure in inactive adults with metabolic syndrome - a six-month exploratory RCT.

Autor: Norha J; Turku PET Centre, University of Turku and Turku University Hospital, Turku, Finland. jooa.norha@utu.fi., Sjöros T; Turku PET Centre, University of Turku and Turku University Hospital, Turku, Finland., Garthwaite T; Turku PET Centre, University of Turku and Turku University Hospital, Turku, Finland., Laine S; Turku PET Centre, University of Turku and Turku University Hospital, Turku, Finland., Saarenhovi M; Department of Clinical Physiology and Nuclear Medicine, University of Turku and Turku University Hospital, Turku, Finland., Kallio P; Department of Clinical Physiology and Nuclear Medicine, University of Turku and Turku University Hospital, Turku, Finland.; Paavo Nurmi Centre and Unit for Health and Physical Activity, University of Turku, Turku, Finland., Laitinen K; Institute of Biomedicine, University of Turku, Turku, Finland., Houttu N; Institute of Biomedicine, University of Turku, Turku, Finland., Vähä-Ypyä H; The UKK Institute for Health Promotion Research, Tampere, Finland., Sievänen H; The UKK Institute for Health Promotion Research, Tampere, Finland., Löyttyniemi E; Department of Biostatistics, University of Turku and Turku University Hospital, Turku, Finland., Vasankari T; The UKK Institute for Health Promotion Research, Tampere, Finland.; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Knuuti J; Turku PET Centre, University of Turku and Turku University Hospital, Turku, Finland., Kalliokoski KK; Turku PET Centre, University of Turku and Turku University Hospital, Turku, Finland., Heinonen IHA; Turku PET Centre, University of Turku and Turku University Hospital, Turku, Finland.
Jazyk: angličtina
Zdroj: Journal of human hypertension [J Hum Hypertens] 2024 Apr; Vol. 38 (4), pp. 314-321. Date of Electronic Publication: 2024 Jan 24.
DOI: 10.1038/s41371-024-00894-6
Abstrakt: Evidence on the long-term effects of reducing sedentary behaviour (SB) on blood pressure (BP) is scarce. Therefore, we performed a sub-analysis of the BP effects of a six-month intervention that aimed at reducing SB by 1 h/day and replacing it with non-exercise activities. Sixty-four physically inactive and sedentary adults with metabolic syndrome (58% female, 58 [SD 7] years, BP 143/88 [16/9] mmHg, SB 10 [1] h/day) were randomised into intervention (INT, n = 33) and control (CON, n = 31) groups. Resting BP and BP at each stage during and after a graded maximal bicycle ergometer test were measured before and after the intervention. SB, standing, moderate-to-vigorous physical activity (MVPA), and light physical activity (LPA) were measured in six-second intervals at baseline and during the whole six-month intervention using hip-worn accelerometers. The analyses were adjusted for BP medication status. The intervention resulted in a 40 min/day reduction in SB and concomitant 20 min/day increase in MVPA. Resting systolic BP was lower in the CON group before and after the intervention. No group x time interactions were observed in resting BP or BP during exercise at submaximal or maximal intensities, or during recovery. The changes in LPA and MVPA were inversely correlated with the changes in BP during light-to-moderate intensity exercise. An intervention that resulted in a 40 min/day reduction in SB for six months was not sufficient at influencing BP at rest, during or after exercise in adults with metabolic syndrome. However, successfully increasing LPA or MVPA might lower BP during light-to-moderate-intensity activities.
(© 2024. The Author(s).)
Databáze: MEDLINE
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