Longitudinal plasma proteomics in CAR T-cell therapy patients implicates neutrophils and NETosis in the genesis of CRS.

Autor: Flora C; Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI., Olesnavich M; Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI., Zuo Y; Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI., Sandford E; Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI., Madhukar R; Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI., Rozwadowski M; Department of Pediatrics, Division of Pediatric Hematology Oncology, University of Michigan, Ann Arbor, MI., Sugur K; Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI., Ly A; Johns Hopkins University School of Medicine, Baltimore, MD., Canbaz AA; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD., Shedeck A; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD., Li G; Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI., Geer MJ; Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI., Yanik GA; Department of Pediatrics, Division of Pediatric Hematology Oncology, University of Michigan, Ann Arbor, MI., Ghosh M; Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI., Frame DG; Department of Clinical Pharmacy, College of Pharmacy, University of Michigan, Ann Arbor, MI., Bonifant CL; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD.; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD., Jain T; Johns Hopkins University School of Medicine, Baltimore, MD.; Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD., Knight JS; Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI., Choi SW; Department of Pediatrics, Division of Pediatric Hematology Oncology, University of Michigan, Ann Arbor, MI.; Rogel Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI., Tewari M; Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI.; Rogel Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI.; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI.; Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI.; VA Ann Arbor Healthcare System, Ann Arbor, MI.
Jazyk: angličtina
Zdroj: Blood advances [Blood Adv] 2024 Mar 26; Vol. 8 (6), pp. 1422-1426.
DOI: 10.1182/bloodadvances.2023010728
Databáze: MEDLINE