The seroprevalence of toxocariasis and related risk factors in children in Ho Chi Minh City, Vietnam: results from a school-based cross-sectional study.

Autor:	Ha TV; Department of Pediatrics, Faculty of Medicine, Pham Ngoc Thach University of Medicine, 2 Duong Quang Trung Str., Dist. 10, 72500, Ho Chi Minh City, Vietnam.; Department of Gastroenterology, Children's Hospital 2, 14 Ly Tu Trong Str., Dist. 1, 71000, Ho Chi Minh City, Vietnam., Vo TTN; Department of Family Medicine, Faculty of Medicine, Pham Ngoc Thach University of Medicine, 2 Duong Quang Trung Str., Dist. 10, 72500, Ho Chi Minh City, Vietnam., Dang DKH; Pham Ngoc Thach University of Medicine, 2 Duong Quang Trung Str., Dist. 10, 72500, Ho Chi Minh City, Vietnam., Tran YML; Pham Ngoc Thach University of Medicine, 2 Duong Quang Trung Str., Dist. 10, 72500, Ho Chi Minh City, Vietnam., Kim TV; Department of Epidemiology, Faculty of Public Health, Pham Ngoc Thach University of Medicine, 2 Duong Quang Trung Str., Dist. 10, 72500, Ho Chi Minh City, Vietnam., Le DH; Department of Epidemiology, Faculty of Public Health, Pham Ngoc Thach University of Medicine, 2 Duong Quang Trung Str., Dist. 10, 72500, Ho Chi Minh City, Vietnam., Do LT; Department of Epidemiology, Faculty of Public Health, Pham Ngoc Thach University of Medicine, 2 Duong Quang Trung Str., Dist. 10, 72500, Ho Chi Minh City, Vietnam., Tang HK; Department of Epidemiology, Faculty of Public Health, Pham Ngoc Thach University of Medicine, 2 Duong Quang Trung Str., Dist. 10, 72500, Ho Chi Minh City, Vietnam.
Jazyk:	angličtina
Zdroj:	Transactions of the Royal Society of Tropical Medicine and Hygiene [Trans R Soc Trop Med Hyg] 2024 Jun 04; Vol. 118 (6), pp. 384-390.
DOI:	10.1093/trstmh/trad102
Abstrakt:	Background: Children are especially vulnerable to Toxocara infection and its severe complications; however, there have not been any published data on the disease prevalence and treatment effectiveness in the population of Vietnamese children. This study was conducted to determine the prevalence of toxocariasis and explore factors associated with Toxocara infection in children aged 3-15 y in Ho Chi Minh City, Vietnam. Methods: We conducted a cross-sectional study using a multistage cluster sampling approach in public schools. Blood samples were collected, and toxocariasis cases were confirmed, based on a history of contact with dogs/cats and positive anti-Toxocara antibody detection via ELISA. We calculated the percentage of seropositive children across gender, grade levels, districts and caregiver education. Multiple regression models were employed to identify potential risk factors. Results: Anti-Toxocara antibodies were found in 14.2% of the 986 children studied. Significant variations in seropositivity were observed across grade levels, districts and caregiver education levels. Multivariable analysis identified caregiver education, contact with dogs/cats and improper handling of pet feces as seropositivity risk factors. Conclusion: This was the first community-based prevalence study of toxocariasis in a pediatric population in Vietnam. Implementation of preventive measures such as public education, routine fecal examinations and chemotherapeutic treatment of animals is highly recommended. (© The Author(s) 2024. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene.)
Databáze:	MEDLINE
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