Simultaneous Electrochemical Detection of Dopamine and Uric Acid via Au@Cu-Metal Organic Framework.

Autor: Zhou F; Department of Chemistry, Faculty of Science, University Putra Malaysia, 43400, UPM Serdang, Selangor, Malaysia., Lim HN; Department of Chemistry, Faculty of Science, University Putra Malaysia, 43400, UPM Serdang, Selangor, Malaysia.; Foundry of Reticular Materials for Sustainability (FORMS) Laboratory, Institute of Nanoscience and Nanotechnology, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia., Ibrahim I; Foundry of Reticular Materials for Sustainability (FORMS) Laboratory, Institute of Nanoscience and Nanotechnology, Universiti Putra Malaysia, 43400 UPM, Serdang, Selangor, Malaysia.; Functional Nanotechnology Devices Laboratory (FNDL), Institute of Nanoscience and Nanotechnology, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia., Endot NA; Department of Chemistry, Faculty of Science, University Putra Malaysia, 43400, UPM Serdang, Selangor, Malaysia., Malek EA; Department of Chemistry, Faculty of Science, University Putra Malaysia, 43400, UPM Serdang, Selangor, Malaysia., Gowthaman NSK; School of Engineering, Monash University Malaysia, Jalan Lagoon Selatan, 47500, Bandar Sunway, Selangor, Malaysia.
Jazyk: angličtina
Zdroj: ChemPlusChem [Chempluschem] 2024 May; Vol. 89 (5), pp. e202300686. Date of Electronic Publication: 2024 Feb 08.
DOI: 10.1002/cplu.202300686
Abstrakt: The incorporation of noble metals with metal-organic frameworks (MOFs) are conducive to the simultaneous electrochemical detection of analytes owing to multiple accessible reaction sites. Herein, Au@Cu-metal organic framework (Au@Cu-MOF) is successfully synthesized and modified as a screen-printed carbon electrode (SPCE), which serves as an excellent electrocatalyst for the oxidation of dopamine (DA) and uric acid (UA). The sensor shows a linear range from 10 μM to 1000 μM, with sensitivity and detection limit of 0.231 μA μM -1  cm -2 and 3.40 μM for DA, and 0.275 μA μM -1  cm -2 and 10.36 μM for UA. Au@Cu-MOF could realize the individual and simultaneous electrochemical sensing of DA and UA, with distinguishable oxidation peak potentials. Moreover, it exhibits reproducibility, repeatability, and stability. Ultimately, the sensor provides an avenue for an ultrasensitive label-free electrochemical detection of DA and UA.
(© 2024 Wiley-VCH GmbH.)
Databáze: MEDLINE
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