Ilmenite-derived titanic acid species: exploring their outstanding light-independent antibacterial activity.

Autor: Wickramasinghe ND; Centre for Advanced Materials and Devices (CAMD), Department of Chemistry, University of Colombo Colombo 00300 Sri Lanka rohini@chem.cmb.ac.lk +94714406263., Sampath AHJ; Centre for Advanced Materials and Devices (CAMD), Department of Chemistry, University of Colombo Colombo 00300 Sri Lanka rohini@chem.cmb.ac.lk +94714406263., Nanayakkara CM; Department of Plant Sciences, University of Colombo Colombo 00300 Sri Lanka., de Silva KMN; Centre for Advanced Materials and Devices (CAMD), Department of Chemistry, University of Colombo Colombo 00300 Sri Lanka rohini@chem.cmb.ac.lk +94714406263., de Silva RM; Centre for Advanced Materials and Devices (CAMD), Department of Chemistry, University of Colombo Colombo 00300 Sri Lanka rohini@chem.cmb.ac.lk +94714406263.
Jazyk: angličtina
Zdroj: RSC advances [RSC Adv] 2024 Jan 22; Vol. 14 (5), pp. 3379-3389. Date of Electronic Publication: 2024 Jan 22 (Print Publication: 2024).
DOI: 10.1039/d3ra07262b
Abstrakt: The emergence of resistance in detrimental pathogenic bacteria towards well-recognized antibiotics has greatly impacted global medicine, consequently exploring potent antibacterial compounds is becoming a potential area of research. Although photocatalytic metal oxides have been extensively explored in this regard, their applicability is diminished due to the requirement of photon energy. Therefore, in our study, we explored the light-independent antibacterial effect of two unexplored titanium species, known as metatitanic acid (MTA) and potassium titanate, against Staphylococcus aureus , Escherichia coli , and Pseudomonas spp. using the disk diffusion method in Luria-Bertani agar medium, where the well-known antibiotic, gentamicin, was used as the positive control. These two titanium compounds were readily synthesized through a novel process which was originally developed for the extraction of TiO 2 from ilmenite. The synthesized MTA was characterized using FT-IR, Raman spectroscopy, XRD, TGA, UV-visible spectroscopy, and SEM. According to our findings, both MTA and potassium titanate exhibited superior light-independent antibacterial properties, where for some concentrations, the effect was even greater than gentamicin. However, nano-TiO 2 totally failed as an antibacterial compound against the tested three strains under dark conditions.
Competing Interests: The authors declare no conflict of interest.
(This journal is © The Royal Society of Chemistry.)
Databáze: MEDLINE
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