Topical anesthetics for needle-related pain in adults and children (TOPIC): a mini-review.

Autor: Le May S; Institut TransMedTech, CHU Sainte-Justine Research Center, Montreal, QC, Canada.; Faculty of Nursing, University of Montreal, Montreal, QC, Canada.; Faculty of Dental Medicine, University of Montreal, Montreal, QC, Canada., Wu W; Institut TransMedTech, CHU Sainte-Justine Research Center, Montreal, QC, Canada.; Faculty of Dental Medicine, University of Montreal, Montreal, QC, Canada.; Department of Dental Medicine, CHU Sainte-Justine, Montreal, QC, Canada., Francoeur M; Institut TransMedTech, CHU Sainte-Justine Research Center, Montreal, QC, Canada., Dodin P; Medical Librairies, Direction de l'enseignement, CHU Sainte-Justine, Montreal, QC, Canada., Doyon-Trottier E; Emergency Department, CHU Sainte-Justine, Montreal, QC, Canada.; Faculty of Medicine, University of Montreal, Montreal, QC, Canada., Hung N; Institut TransMedTech, CHU Sainte-Justine Research Center, Montreal, QC, Canada.; Faculty of Medicine, University of Montreal, Montreal, QC, Canada., Guingo E; Institut TransMedTech, CHU Sainte-Justine Research Center, Montreal, QC, Canada.; Department of Creation and New Medias, University of Quebec in Abitibi-Temiscamingue, Rouyn-Noranda, QC, Canada., Vu AK; Faculty of Dental Medicine, University of Montreal, Montreal, QC, Canada., Sylfra A; Faculty of Medicine, University of Montreal, Montreal, QC, Canada., Lessard L; Institut TransMedTech, CHU Sainte-Justine Research Center, Montreal, QC, Canada., Cara-Slavich S; Institut TransMedTech, CHU Sainte-Justine Research Center, Montreal, QC, Canada.; Faculty of Nursing, University of Montreal, Montreal, QC, Canada., DeKoven K; Faculty of Medicine, University of Montreal, Montreal, QC, Canada.; Department of Anesthesiology, CHU Sainte-Justine, Montreal, QC, Canada.
Jazyk: angličtina
Zdroj: Frontiers in pain research (Lausanne, Switzerland) [Front Pain Res (Lausanne)] 2024 Jan 08; Vol. 4, pp. 1350578. Date of Electronic Publication: 2024 Jan 08 (Print Publication: 2023).
DOI: 10.3389/fpain.2023.1350578
Abstrakt: Purpose: Healthcare professionals (HCP) perform various needle procedures that can be distressing and painful for children and adults. Even though many strategies have been proven effective in reducing distress and pain, topical anesthetic use before needle procedures is uncommon. However, there are limited studies in the existing literature comparing specifically liposomal lidocaine and tetracaine hydrochloride topical creams.
Source: This systematic review analyzed studies on the use of two anesthetic creams, Liposomal Lidocaine (Maxilene®) and Tetracaine hydrochloride (Ametop™), in children and adults undergoing a needle-related procedure. Databases searched: PubMed, CINAHL, ClinicalTrials. Only randomized controlled trials (RCT) and Controlled Clinical Trials (CCT) studies were included. Cochrane Collaboration's Risk of Bias assessment tool was used. Strictly minimally invasive procedures were included to standardize different skin needle interventions.
Principal Findings: Only one study with 60 participants was available to be included in this review. No statistically significant difference was found in the mean pain score among both interventions. The outcomes of self-reported distress during cannulation and on HCP satisfaction were not reported. However, physiological characteristics associated with stress/anxiety and on cannulation success rate were reported and did not show statistical significance.
Conclusion: Little to no evidence regarding the most efficient cream between liposomal lidocaine and tetracaine hydrochloride for pain management during needle-related procedures was found. Further studies, particularly RCT with larger sample sizes and standardized outcome measures, are needed to confirm the relative efficacy of either anesthetic cream.
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(© 2024 Le May, Wu, Francoeur, Dodin, Doyon-Trottier, Hung, Guingo, Vu, Sylfra, Lessard, Cara-Slavich and DeKoven.)
Databáze: MEDLINE