Body mass index z-scores in the first 2 years of life were associated with adverse metabolic and anthropometric outcomes at 3 years of age.

Autor: Jakobsen ME; Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark.; The National Research Center for the Working Environment, Copenhagen, Denmark., Stentebjerg LL; Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Tanvig MH; Department of Gynecology and Obstetrics, Odense University Hospital, Odense, Denmark., Jørgensen JS; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Gynecology and Obstetrics, Odense University Hospital, Odense, Denmark., Ovesen PG; Department of Obstetrics and Gynecology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.; Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark., Christesen HT; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Hans Christian Andersen Children's Hospital, Odense University Hospital, Odense, Denmark., Jensen DM; Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Gynecology and Obstetrics, Odense University Hospital, Odense, Denmark., Vinter CA; Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.; Department of Gynecology and Obstetrics, Odense University Hospital, Odense, Denmark.
Jazyk: angličtina
Zdroj: Acta paediatrica (Oslo, Norway : 1992) [Acta Paediatr] 2024 May; Vol. 113 (5), pp. 1068-1075. Date of Electronic Publication: 2024 Jan 23.
DOI: 10.1111/apa.17122
Abstrakt: Aim: We investigated associations between body mass index (BMI) z-scores for children aged 0-2 years and the BMI z-scores, body fat percentage and metabolic risk factors at 3 years of age.
Methods: This was a secondary analysis of the Lifestyle in Pregnancy and Offspring randomised controlled trial, carried out at two university hospitals in Denmark. It comprised 149 mothers with BMI ≥30 kg/m 2 who did or did not receive a lifestyle intervention during pregnancy and a reference group of 97 mothers with normal-weight, with follow-up of their 3-year-old offspring. The children in these three groups were pooled for the data analyses, due to similar characteristics between groups. The BMI z-scores were calculated at 5 weeks, 5 months and 1, 2 and 3 years, using Danish reference groups. Their anthropometrics and metabolic outcomes were examined at 3 years of age.
Results: BMI z-scores at 5 months to 2 years were associated with BMI z-scores and body fat percentage at 3 years of age and BMI z-scores were not associated with metabolic risk factors at 3 years.
Conclusion: BMI z-scores from 5 weeks of age were associated with adverse anthropometric outcomes but not with metabolic risk factors at 3 years of age.
(© 2024 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica.)
Databáze: MEDLINE
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