Effect of curcumin, betadine and chlorhexidine in gingival wound healing.

Autor: Agrawal A; Department of Conservative and Endodontics, Buddha Institute of Dental Sciences and Hospital, Patna, Bihar, India., Rashmi Kiran E; Department of Oral Medicine and Radiology, Bhabha College of Dental Sciences, Bhopal, MP, India., Deepika S; Department of Conservative Dentistry & Endodontics, Desh Bhagat Dental College & Hospital, Mandi Gobindgarh, Punjab, India., Kumar P; Department of Oral Pathology & Microbiology, Government College of Dentistry, Indore, M.P., India., Kochar D; Department of Periodontology, M.M. College of Dental Sciences & Research, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana, India., Ruhi S; Oral Medicine and Radiology, MNDAV Dental College and Hospital, Tatul, Oachghat, Solan, Himachal Pradesh, India., Gupta B; Department of Periodontics, MGM Dental College, Navi Mumbai, India., Paiwal K; Department of Oral & Maxillofacial Pathology, Daswani Dental College & Research Center, Kota, India.
Jazyk: angličtina
Zdroj: Bioinformation [Bioinformation] 2023 Dec 31; Vol. 19 (12), pp. 1153-1158. Date of Electronic Publication: 2023 Dec 31 (Print Publication: 2023).
DOI: 10.6026/973206300191153
Abstrakt: The effect of chlorhexidine (CHX) digluconate, Betadine (BET), curcumin (CUR) on gingival wound healing is of interest to dental practitioners. Hence, we studied the average fibroblast viability % for each of the concentrations of CUR, BET and CHX over various time durations. It was found that mean percentage of viability of fibroblasts is high in CUR and low in CHX at all time periods while the mean percentage of viability of fibroblasts in BET 1% was greater than CHX but lower than CUR at all time periods. Thus, curcumin at a concentration of 0.003% demonstrates the least cytotoxicity for fibroblasts. Hence, it is the most effective bacterial suppression, and the best wound healing.
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Databáze: MEDLINE