Quantitative Analysis of Inner, Middle, and Outer Retinal Thickness by Optical Coherence Tomography in Children and Adolescents.

Autor:	Ghassemi F; Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.; Retina and Vitreous Service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran., Salari F; Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran., Hatami V; Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran., Bazvand F; Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.; Retina and Vitreous Service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran., Shamouli H; Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran., Mohebbi M; Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.; Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran., Sabour S; Department of Clinical Epidemiology, School of Health and Safety, Safety Promotion and Injury Prevention Research Center, Tehran, Iran.; Department of Clinical Epidemiology, School of Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Jazyk:	angličtina
Zdroj:	Journal of current ophthalmology [J Curr Ophthalmol] 2023 Dec 21; Vol. 35 (2), pp. 182-189. Date of Electronic Publication: 2023 Dec 21 (Print Publication: 2023).
DOI:	10.4103/joco.joco_141_23
Abstrakt:	Purpose: To describe the variance of inner, middle, and outer retinal layer thicknesses (IRT, MRT, and ORT) at the macular area in children and adolescents with normal eyes in different age groups. Methods: This cross-sectional study enrolled subjects aged 5-18 years with normal eyes. The macula was scanned by optical coherence tomography (6 mm × 6 mm AngioScan-Optovue). Four age groups were defined (≤7, 7-10, 11-14, and ≥14 years). The influences of age and gender were analyzed. Results: One hundred and thirty-nine eyes of 69 subjects with a mean age of 10.92 ± 3.51 years were registered. The mean whole macular thickness (MT) was 297.32 ± 11.05 in males and 303.197 ± 13.32 in females ( P = 0.01, t -test). The MT in each aging group was 301.47 ± 2.5, 295.53 ± 1.71, 300.81 ± 2.12, and 298.6 ± 1.87, subsequently ( P = 0.17, analysis of variance test). Significant differences were found between the sexes at the perifoveal area and mainly in IRT. No correlation between eyes was noted. We observed that the RT fluctuates during growth and that gender has some influence on the evolution of RT. IRT and MRT changed reciprocally in all macular areas, whereas ORT expanded in all age groups of children and adolescents. Conclusions: No subsegmental retinal thickness difference between eyes was observed in pediatric groups in this study, while gender had some influence on perifoveal IRT. Despite the fact that this study is not a longitudinal study, we can get some insight into the developmental changes in retinal thickness and its clinical applications in children and adolescents. Competing Interests: There are no conflicts of interest. (Copyright: © 2023 Journal of Current Ophthalmology.)
Databáze:	MEDLINE
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