[Prevalence and risk factors for methicillin-resistant Staphylococcus aureus infection in children].

Autor:	Marín Oliván P; Paula Marín Oliván, Servicio de Pediatría, Hospital Clínico Universitario, Valencia, Avenida de Blasco Ibáñez, 17, 46010 Valencia, Spain. paumaol@hotmail.com., Ferrando Monleón S, Bretón-Martínez JR, Piolatti Luna A, Hernández Monleón I, Fuertes Latasa C, Navarro Ortega D, Colomina Rodríguez J
Jazyk:	Spanish; Castilian
Zdroj:	Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia [Rev Esp Quimioter] 2024 Apr; Vol. 37 (2), pp. 170-175. Date of Electronic Publication: 2024 Jan 22.
DOI:	10.37201/req/113.2023
Abstrakt:	Objective: The objectives of this work were to know the prevalence of methicillin-resistant S. aureus (MRSA) infections in the paediatric population of our health department, to describe the risk factors for infection by MRSA compared to those produced by methicillin-susceptible S. aureus (MSSA) and to know the antibiotic sensitivity profile of MRSA and MSSA isolates. Methods: A retrospective, descriptive and analytical study of infections produced by MRSA versus those produced by MSSA was carried out during the years 2014 to 2018. Risk factors for MRSA infection were studied using a binary logistic regression model. Results: 162 patients with S. aureus infections were identified. Of these, 25 (15.4%) were MRSA. The highest percentages of MRSA infection occurred among children who required hospital admission (23.4%). In the univariate analysis the need of hospital admission, antibiotic treatment in the last 3 months, the kind of infection and past MRSA infection or colonisation reached statistical significance. However, only the need of hospital admission and antibiotic treatment in the last 3 months maintained statistical significance in the binary logistic regression model. Correct antibiotic treatment was only prescribed in 26.7% of the MRSA infection cases admitted to the hospital. Conclusions: Our results suggest the need to review empirical local treatment regimen using drugs active against MRSA in infections of probable staphylococcal origin admitted to the hospital, especially if they have received antibiotic treatment in the last 3 months. (©The Author 2024. Published by Sociedad Española de Quimioterapia. This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (CC BY-NC 4.0)(https://creativecommons.org/licenses/by-nc/4.0/).)
Databáze:	MEDLINE
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