Cerebellar-Induced Aphasia After Stroke: Evidence for the "Linguistic Cerebellum".

Autor: Satoer D; Department of Neurosurgery, Erasmus MC University Medical Center, Dr. Molewaterplein 40, room Na-2106, 3015, GD, Rotterdam, The Netherlands. d.satoer@erasmusmc.nl., Koudstaal PJ; Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., Visch-Brink E; Department of Neurosurgery, Erasmus MC University Medical Center, Dr. Molewaterplein 40, room Na-2106, 3015, GD, Rotterdam, The Netherlands.; Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands., van der Giessen RS; Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Jazyk: angličtina
Zdroj: Cerebellum (London, England) [Cerebellum] 2024 Aug; Vol. 23 (4), pp. 1457-1465. Date of Electronic Publication: 2024 Jan 20.
DOI: 10.1007/s12311-024-01658-1
Abstrakt: The cerebellum is traditionally known to subserve motor functions. However, for several decades, the concept of the "cerebellar cognitive affective syndrome" has evolved. Studies in healthy participants and patients have confirmed the cerebellar role in language. The exact involvement of the cerebellum regarding cerebellar aphasia remains uncertain. We included 43 cerebellar stroke patients who were tested at 3 months post-onset with the Boston Naming Test (BNT), the Token Test (TT), and the Diagnostic Instrument for Mild Aphasia (DIMA). Lesion side (left/right) and volume (cm 3 ) were investigated. Patients significantly deviated on the following: BNT (p<0.001), TT (p<0.05), DIMA subtests: sentences repetition (p=0.001), semantic odd-picture-out (p<0.05), sentence completion (p<0.05) without an effect of lesion location (left/right) or volume (cm 3 ) (p>0.05). Our clinical study confirms a non-lateralized cerebellar aphasia post-stroke, characterized by impairments in word retrieval, phonology, semantics, and syntax resembling cerebral-induced aphasia. The integral cerebellum appears to interact with eloquent cortico-subcortical language areas.
(© 2024. The Author(s).)
Databáze: MEDLINE
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