The uncharted territory of NAD + -capped RNA.

Autor: Ma Q; Zhejiang University, College of Biosystems Engineering and Food Science, Hangzhou 310058, China., Liu J; MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, China., Hu H; Department of Botany and Plant Sciences, Institute of Integrative Genome Biology, University of California, Riverside, CA 92521, USA. Electronic address: haohu@ucr.edu., Luo Z; Zhejiang University, College of Biosystems Engineering and Food Science, Hangzhou 310058, China; Ningbo Innovation Center, Zhejiang University, Ningbo 315100, China. Electronic address: luozisheng@zju.edu.cn.
Jazyk: angličtina
Zdroj: Trends in cell biology [Trends Cell Biol] 2024 May; Vol. 34 (5), pp. 355-359. Date of Electronic Publication: 2024 Jan 18.
DOI: 10.1016/j.tcb.2023.12.005
Abstrakt: The critical redox cofactor NAD + was recently reported to serve as an RNA cap in both eukaryotes and prokaryotes. However, its reversible regulation and biological functions remain unclear. Here, we provide insights into its discovery, capping and decapping mechanisms, for further discovery of their potential functional implications.
Competing Interests: Declaration of interests The authors have no interests to declare.
(Copyright © 2023 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: