In vitro virucidal activity of a commercial disinfectant against viruses of domestic animals and poultry.
| Autor: | Sobhy NM; Department of Veterinary Population Medicine, University of Minnesota, Saint Paul, MN, United States.; Department of Animal Medicine, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Sharkia, Egypt., Quinonez-Munoz A; Department of Veterinary Population Medicine, University of Minnesota, Saint Paul, MN, United States., Aboubakr HA; Department of Veterinary Population Medicine, University of Minnesota, Saint Paul, MN, United States., Youssef CRB; Department of Veterinary Population Medicine, University of Minnesota, Saint Paul, MN, United States.; Department of Microbiology and Immunology, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt., Ojeda-Barría G; Veterquimica S.A., Santiago, Chile., Mendoza-Fernández J; Veterquimica S.A., Santiago, Chile., Goyal SM; Department of Veterinary Population Medicine, University of Minnesota, Saint Paul, MN, United States. |
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| Jazyk: | angličtina |
| Zdroj: | Frontiers in veterinary science [Front Vet Sci] 2024 Jan 04; Vol. 10, pp. 1276031. Date of Electronic Publication: 2024 Jan 04 (Print Publication: 2023). |
| DOI: | 10.3389/fvets.2023.1276031 |
| Abstrakt: | Outbreaks of viral diseases in animals are a cause of concern for animal welfare and economics of animal production. One way to disrupt the cycle of infection is by combating viruses in the environment and prohibiting them from being transmitted to a new host. Viral contamination of the environment can be reduced using well-tested and efficacious disinfectants. Duplalim is a commercially available disinfectant consisting of 12% glutaraldehyde and 10% quaternary ammonium compounds. We evaluated this disinfectant for its efficacy against several viruses in poultry ( n = 3), pigs ( n = 5), dogs ( n = 2), and cattle ( n = 4). In suspension tests, 1:100 dilution of Duplalim was found to inactivate more than 99% of these 14 viruses in 15 min or less. The titers of a majority of these viruses decreased by ≥99.99% in <60 min of contact time. In conclusion, the ingredient combination in Duplalim is very effective in inactivating common viruses of domestic animals and poultry. Competing Interests: SG laboratory was employed by the company Veterquimica S.A. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2024 Sobhy, Quinonez-Munoz, Aboubakr, Youssef, Ojeda-Barría, Mendoza-Fernández and Goyal.) |
| Databáze: | MEDLINE |
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