COMPArison of Multi-Point Pacing and ConvenTional Cardiac Resynchronization Therapy Through Noninvasive Hemodynamics Measurement: Short- and Long-Term Results of the COMPACT-MPP Study.
Autor: | Passafaro F; Division of Cardiology, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy., Rapacciuolo A; Division of Cardiology, Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy., Ruocco A; Division of Cardiology, Emergency Department, AORN Cardarelli, Naples, Italy., Ammirati G; Division of Cardiology, Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy., Crispo S; Division of Cardiology, Emergency Department, AORN Cardarelli, Naples, Italy., Pasceri E; Division of Cardiology, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy., Santarpia G; Division of Cardiology, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy., Mauro C; Division of Cardiology, Emergency Department, AORN Cardarelli, Naples, Italy., Esposito G; Division of Cardiology, Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy., Indolfi C; Division of Cardiology, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy., Curcio A; Division of Cardiology, Department of Pharmacy, Health Sciences and Nutrition, University of Calabria, Cosenza, Italy. Electronic address: antonio.curcio.cardio@unical.it. |
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Jazyk: | angličtina |
Zdroj: | The American journal of cardiology [Am J Cardiol] 2024 Mar 15; Vol. 215, pp. 42-49. Date of Electronic Publication: 2024 Jan 17. |
DOI: | 10.1016/j.amjcard.2023.12.057 |
Abstrakt: | Invasive hemodynamic studies have shown improved left ventricular (LV) performances when cardiac resynchronization therapy/defibrillator is delivered through multipoint pacing (MPP). Nowadays, strategies have become available that allow studying the same hemodynamic parameters at a noninvasive level. The aim of the present study was to evaluate the clinical implication of using a patient-tailored approach for cardiac resynchronization therapy programming based on noninvasively assessed LV hemodynamics to identify the best biventricular pacing modality between standard single-site pacing (STD) and MPP for each patient. Therefore, 51 patients with heart failure (age 69 ± 9 years, 35 men, 27% ischemic etiology) implanted with cardiac resynchronization therapy/defibrillator underwent noninvasive LV function assessment through photoplethysmography before hospital discharge for addressing dP/dt and stroke volume in both pacing modalities (STD and MPP). The modality that performed better in terms of hemodynamic improvement was permanently programmed. Global longitudinal strain (GLS) was also assessed, and repeated at 3 months. Compared with intrinsic rhythm (928 ± 486 mm Hg/s), dP/dt Competing Interests: Declaration of competing interest The authors have no competing interests to declare. (Copyright © 2024 Elsevier Inc. All rights reserved.) |
Databáze: | MEDLINE |
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