| Autor: |
Patra S; School of Biomedical Engineering, Indian Institute of Technology-BHU, Varanasi 221005, India., Pareek D; School of Biomedical Engineering, Indian Institute of Technology-BHU, Varanasi 221005, India., Gupta PS; School of Biomedical Engineering, Indian Institute of Technology-BHU, Varanasi 221005, India., Wasnik K; School of Biomedical Engineering, Indian Institute of Technology-BHU, Varanasi 221005, India., Singh G; School of Biomedical Engineering, Indian Institute of Technology-BHU, Varanasi 221005, India., Yadav DD; School of Biomedical Engineering, Indian Institute of Technology-BHU, Varanasi 221005, India., Mastai Y; Department of Chemistry, Bar-Ilan University, Ramat-Gan 5290002, Israel., Paik P; School of Biomedical Engineering, Indian Institute of Technology-BHU, Varanasi 221005, India. |
| Abstrakt: |
In this era of advanced technology and innovation, infectious diseases still cause significant morbidity and mortality, which need to be addressed. Despite overwhelming success in the development of vaccines, transmittable diseases such as tuberculosis and AIDS remain unprotected, and the treatment is challenging due to frequent mutations of the pathogens. Formulations of new or existing drugs with polymeric materials have been explored as a promising new approach. Variations in shape, size, surface charge, internal morphology, and functionalization position polymer particles as a revolutionary material in healthcare. Here, an overview is provided of major diseases along with statistics on infection and death rates, focusing on polymer-based treatments and modes of action. Key issues are discussed in this review pertaining to current challenges and future perspectives. |
