Low-Flow, Low-Gradient Severe Aortic Stenosis in patients with preserved or reduced ejection fraction: a systematic literature review.

Autor: Aguilar-Molina O; Cardiology Unit, Universidad del Valle, Cali, Colombia; Hospital Universitario del Valle, Cali, Colombia., Barbosa-Balaguera S; Cardiology Unit, Universidad del Valle, Cali, Colombia; Hospital Universitario del Valle, Cali, Colombia., Campo-Rivera N; Cardiology Unit, Universidad del Valle, Cali, Colombia; Hospital Universitario del Valle, Cali, Colombia., Cabrales-Salcedo Y; Hospital Universitario del Valle, Cali, Colombia., Camacho-Garcia R; Universidad de Cartagena, Cartagena, Colombia., Herrera-Escandón Á; Cardiology Unit, Universidad del Valle, Cali, Colombia; Hospital Universitario del Valle, Cali, Colombia.
Jazyk: angličtina
Zdroj: Current problems in cardiology [Curr Probl Cardiol] 2024 Mar; Vol. 49 (3), pp. 102392. Date of Electronic Publication: 2024 Jan 15.
DOI: 10.1016/j.cpcardiol.2024.102392
Abstrakt: Objectives: A systematic review of the literature was conducted to analyze the current evidence on low-flow, low-gradient severe aortic stenosis. This analysis aimed to differentiate between subgroups of patients with reduced and preserved left ventricular ejection fraction (LVEF).
Methods: After conducting a systematic literature review, 35 observational studies were included. Out of these, 28 were prospective and 7 retrospective. The studies that included a mortality risk stratification of low-flow, low-gradient aortic stenosis (LF- LG AS) with both preserved and reduced LVEF were reviewed.
Results: The importance of considering multiple clinical and echocardiographic variables in diagnostic evaluation and therapeutic decision-making was highlighted.
Conclusions: LF- LG AS, in any of its subgroups, is a common and challenging valve lesion. A careful assessment of severity and, in specific scenarios, a thorough reclassification is important. More high-quality studies are required to more precisely define the classification and prognosis of this entity.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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