| Autor: |
Oliveira Dos Santos CE; Department of Endoscopy, Santa Casa de Caridade Hospital. Bagé, Rio Grande do Sul, Brazil; Department of Endoscopy, Pontifícia Universidade Católica do Rio Grande do Sul. Porto Alegre, Rio Grande do Sul, Brazil., Malaman D; Department of Endoscopy, Santa Casa de Caridade Hospital. Bagé, Rio Grande do Sul, Brazil., Arciniegas Sanmartin ID; Department of Endoscopy, Hospital Mãe de Deus. Porto Alegre, Rio Grande do Sul, Brazil., Aleixo P; Department of Endoscopy, Santa Casa de Caridade Hospital. Bagé, Rio Grande do Sul, Brazil., Lopes CV; Department of Gastroenterology and Endoscopy, Santa Casa Hospital. Porto Alegre, Rio Grande do Sul, Brazil., Pereira-Lima JC; Department of Gastroenterology and Endoscopy, Santa Casa Hospital. Porto Alegre, Rio Grande do Sul, Brazil. |
| Jazyk: |
angličtina |
| Zdroj: |
Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru [Rev Gastroenterol Peru] 2023 Oct-Dec; Vol. 43 (4), pp. 364-367. |
| Abstrakt: |
Plexiform fibromyxoma (PF) is a rare mesenchymal neoplasm of the stomach usually arising in the gastric antrum, and its main differential diagnosis is gastrointestinal stromal tumor. Most common symptoms are hematemesis, anemia. Immunohistochemically, positivity for smooth muscle actin (SMA) and vimentin suggests the diagnosis of PF. We report the case of a 56-year-old female patient with a 30-day history of nausea at presentation 4 years ago. Gastroscopy at that time revealed a subepithelial lesion (SEL) in the gastric antrum, measuring approximately 20 mm in diameter, with leakage of serous fluid after biopsy. Histopathology showed only an inflammatory process. Follow-up gastroscopies were performed 24, 36, and 48 months later, with surveillance biopsy at each follow-up. The last gastroscopies showed changes in lesion appearance, reduction in size, and absence of fluid leakage. Histopathology showed bland spindle cell proliferation, with a vaguely plexiform/multinodular pattern, in a fibromyxoid stroma with an arborizing capillary network without mitoses. The tumor cells were positive for SMA and negative for DOG1, CD117, CD34, S100, desmin, EMA, CD10, calponin, and beta-catenin. The choice of treatment and follow-up depends on the SEL features, but because no cases of malignancy or metastatic disease have previously been reported, the patient chose a conservative approach. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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