Mixed Adeno-Neuroendocrine Neoplasms: Two Cases, One Institution.
| Autor: | Paterson C; Abington Memorial Hospital-Jefferson Health Department of Surgery, Abington, PA. (Drs. Paterson, Perrotti, Mushtaq, and Heilman)., Perrotti G; Abington Memorial Hospital-Jefferson Health Department of Surgery, Abington, PA. (Drs. Paterson, Perrotti, Mushtaq, Heilman)., Mushtaq B; Abington Memorial Hospital-Jefferson Health Department of Surgery, Abington, PA. (Drs. Paterson, Perrotti, Mushtaq, Heilman)., Heilman J; Abington Memorial Hospital-Jefferson Health Department of Surgery, Abington, PA. (Drs. Paterson, Perrotti, Mushtaq, Heilman)., Fassler S; Colon and Rectal Associated Limited, Levy Medical Plaza, Abington, PA. (Dr. Fassler). |
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| Jazyk: | angličtina |
| Zdroj: | CRSLS : MIS case reports from SLS [CRSLS] 2023 Jan 15; Vol. 10 (4). Date of Electronic Publication: 2023 Jan 15 (Print Publication: 2023). |
| DOI: | 10.4293/CRSLS.2023.00045 |
| Abstrakt: | Epithelial tumors with neuroendocrine and nonendocrine components constitute the rare yet aggressive entity of neoplasms of the gastro-entero-pancreatic tract. These tumors were first named "mixed adeno-neuroendocrine carcinomas" (MANECs) by the World Health Organization in 2010 and in 2017 renamed "mixed neuroendocrine non-neuroendocrine neoplasms" (MiNENs). Combined adenocarcinoma and neuroendocrine carcinoma neoplasms are a rare occurrence within the gastrointestinal tract. In this report, we describe two separate cases of mixed rectal adeno-neuroendocrine carcinomas and their treatment. We describe two cases at one institution of mixed neuroendocrine non-neuroendocrine rectal neoplasms. Given the rarity of diagnosis and inconsistencies in both nomenclature and treatment recommendations in the literature, mixed adeno-neuroendocrine carcinoma epidemiology and prognosis are not yet fully understood. Future prospective trials with a focus in management of MiNENs will offer valuable insight into these rare mixed carcinomas. Competing Interests: Conflict of interests: none. (© 2023 by SLS, Society of Laparoscopic & Robotic Surgeons.) |
| Databáze: | MEDLINE |
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