COVID-19 in Children with Chronic Kidney Disease; Does it Differ Much?

Autor:	Baltu D; Pediatric Nephrology, Hacettepe University Faculty of Medicine, Ankara, Turkey., Kurt-Sukur ED; Pediatric Nephrology, Hacettepe University Faculty of Medicine, Ankara, Turkey., Tastemel Ozturk T; Pediatric Nephrology, Hacettepe University Faculty of Medicine, Ankara, Turkey., Gulhan B; Pediatric Nephrology, Hacettepe University Faculty of Medicine, Ankara, Turkey., Ozaltin F; Pediatric Nephrology, Hacettepe University Faculty of Medicine, Ankara, Turkey., Duzova A; Pediatric Nephrology, Hacettepe University Faculty of Medicine, Ankara, Turkey., Topaloglu R; Pediatric Nephrology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Jazyk:	angličtina
Zdroj:	Klinische Padiatrie [Klin Padiatr] 2024 Jan 15. Date of Electronic Publication: 2024 Jan 15.
DOI:	10.1055/a-2207-3153
Abstrakt:	Background: COVID-19 is known to have a mild course in children, however more data on pediatric chronic kidney disease (CKD) is needed. We aimed to assess the incidence and severity of COVID-19 in pediatric CKD patients. Methods: A questionnaire including demographics, COVID-19 history, symptoms, and vaccination status was applied to patients with CKD. We also retrospectively reviewed the presentation and outcomes of SARS-CoV-2 infection in this patient group from March 2020 to December 2021. Results: 220 patients were included, 48 were found to have experienced COVID-19. There was no significant difference regarding age, gender, underlying kidney disease, CKD stage, dialysis status, type or number of immunosuppressive medications, and glomerular filtration rate between patients with and without COVID-19. Most were infected by a household member (43.8%) and during outpatient or inpatient care (18.8%). Four (8.3%) were asymptomatic, and 43 (89.6%) had mild infection. Severe COVID-19 was observed in only one patient. Eleven (22.9%) patients with COVID-19 were previously vaccinated. Acute kidney injury was detected in 4 (8.3%); as stage 1 in all. Median follow-up after COVID-19 was 4.6 months. All patients fully recovered, and no renal disease flare or death was observed. Conclusions: Although the vaccination rate was low in our cohort, the majority of the children with COVID-19 showed a mild course. Along with the vaccination, general precautions seemed to be successful for this population. Competing Interests: The authors declare that they have no conflict of interest. (Thieme. All rights reserved.)
Databáze:	MEDLINE
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