Estrogen and psychosis - a review and future directions.

Autor: Mu E; HER Centre Australia, Central Clinical School, Monash University, Melbourne, Victoria, Australia. Eveline.mu@monash.edu., Gurvich C; HER Centre Australia, Central Clinical School, Monash University, Melbourne, Victoria, Australia., Kulkarni J; HER Centre Australia, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Jazyk: angličtina
Zdroj: Archives of women's mental health [Arch Womens Ment Health] 2024 Dec; Vol. 27 (6), pp. 877-885. Date of Electronic Publication: 2024 Jan 15.
DOI: 10.1007/s00737-023-01409-x
Abstrakt: The link between sex hormones and schizophrenia has been suspected for over a century; however, scientific evidence supporting the pharmacotherapeutic effects of exogenous estrogen has only started to emerge during the past three decades. Accumulating evidence from epidemiological and basic research suggests that estrogen has a protective effect in women vulnerable to schizophrenia. Such evidence has led multiple researchers to investigate the role of estrogen in schizophrenia and its use in treatment. This narrative review provides an overview of the effects of estrogen as well as summarizes the recent work regarding estrogen as a treatment for schizophrenia, particularly the use of new-generation selective estrogen receptor modulators.
Competing Interests: Declarations. Competing interests: The authors declare no competing interests.
(© 2024. The Author(s).)
Databáze: MEDLINE
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