Hypertension among persons living with HIV/AIDS and its association with HIV-related health factors.

Autor: Denu MKI; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, 01655, USA. mawulorm.denu@umassmed.edu., Revoori R; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, 01655, USA., Buadu MAE; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA., Oladele O; Department of Psychiatry, Korle Bu Teaching Hospital, Accra, Ghana., Berko KP; Infectious Disease Unit, Korle Bu Teaching Hospital, Accra, Ghana.
Jazyk: angličtina
Zdroj: AIDS research and therapy [AIDS Res Ther] 2024 Jan 11; Vol. 21 (1), pp. 5. Date of Electronic Publication: 2024 Jan 11.
DOI: 10.1186/s12981-023-00576-2
Abstrakt: Background: Human Immunodeficiency Virus (HIV) infection remains a public health concern in many countries. The increased life expectancy in the post-Antiretroviral Therapy (ART) era has led to an increased risk of cardiovascular disease and death among Persons Living with HIV (PLHIV). Hypertension remains a significant risk factor for cardiovascular disease among PLHIV. Some studies have suggested associations between hypertension among PLHIV and HIV-related health factors.
Objective: To determine the prevalence of hypertension among PLHIV on antiretroviral medications and examine its association with HIV-related health factors.
Methods: A cross-sectional study was conducted among attendants at an adult HIV clinic. 362 study participants were selected by systematic sampling. Data on hypertension diagnosis, HIV-related health factors, sociodemographic and other traditional cardiovascular risk factors were collected using a standardized questionnaire and patient chart review. Multivariate logistic regression model was used to determine the association between hypertension and HIV-related factors, adjusting for other risk factors for hypertension.
Results: The mean age of participants was 47.9 years and majority of participants were female (77.1%). 42% of study participants had been on antiretroviral medications for > 10 years. The prevalence of hypertension was 17.4%. Age > 50 years was associated with higher odds of hypertension (aOR: 3.75, 95%CI 1.68, 8.55, p-value: 0.002). BMI in overweight and obese categories, and a history of comorbid medical conditions (diabetes, hyperlipidemia) were also associated with higher odds of hypertension (aOR: 3. 76, 95%CI 1.44, 9.81, p-value: 0.007), (aOR: 3.17, 95%CI 1.21, 8.32, p-value: 0.019) and (aOR: 14.25, 95%CI 7.41, 27.41, p-value: < 0.001) respectively. No HIV-related health factors were associated with hypertension.
Conclusion: Hypertension was a common condition among PLHIV on antiretroviral medications. No HIV-related health factors were associated with hypertension. Traditional risk factors associated with hypertension were increased age > 50 years, increased BMI, and a history of comorbid medical conditions.
(© 2023. The Author(s).)
Databáze: MEDLINE
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