Clinical features, socioeconomic status, management, short and long-term outcomes of patients with acute myocardial infarction: Phase I results of PEACE MENA registry.

Autor: Al Saleh A; Department of Cardiac Sciences, King Fahad Cardiac Center, College of Medicine, King Saud Medical City, King Saud University, Riyadh, Saudi Arabia., Jamee A; Nassar Medical Complex Hospital, Ministry of Health, Khan Younes, Gaza Strip, Palestine.; Al-Quds Hospital, Gaza, Palestine., Sulaiman K; National Heart Center, Royal Hospital, Muscat, Oman., Sobhy M; International Cardiac Center (ICC), Alexandria, Egypt., Gamra H; Research Laboratory LR, Fattouma Bourguiba University Hospital, University of Monastir, Monastir, Tunisia., Alkindi F; Heart Hospital, Hamad Medical Corporation, Doha, Qatar., Benkhedda S; Cardiology Department, Mustapha Hospital, COCRG Laboratory University Benyoucef Benkhedda, Algiers, Algeria., Al-Motarreb A; Faculty of Medicine, Sana'a University, Sana'a, Yemen., Amin MI; Mohamed Bin Khalifa Cardiac Centre, Awali, Bahrain., Almahmeed W; Heart and Vascular Institute, Cleveland Clinic Abu Dhabi, United Arab Emirate., Hammoudeh A; Cardiology Department, Istishari Hospital, Amman, Jordan., Skouri H; Cardiology Division, Internal Medicine Department at American University of Beirut Medical Center, Beirut, Lebanon., Farhan HA; Iraqi Board for Medical Specializations, Scientific Council of Cardiology. Baghdad Heart Center, Medical City, Baghdad, Iraq., Al Jarallah M; Sabah Al Ahmed Cardia Center, Kuwait City, Kuwait., Fellat N; IBN SINA University Hospital, Rabat, Morocco., Panduranga P; National Heart Center, Royal Hospital, Muscat, Oman., Alnajm BK; Al Nahdha Hospital, Muscat, Oman., Abdelhamid M; Faculty of Medicine, Kasr Al Ainy Hospital, Cairo University, Giza Governorate, Egypt., Refaat R; International Cardiac Center (ICC), Alexandria, Egypt., Amor H; Taher Sfar University Hospital, Mahdia, Tunisia., Messaous S; Research Laboratory LR, Fattouma Bourguiba University Hospital, University of Monastir, Monastir, Tunisia., Ahmed HS; Heart Hospital, Hamad Medical Corporation, Doha, Qatar., Chibane A; Internal Medicine and Cardiology Department, CHU Douéra, Algiers, University Saad Dahlab, Blida, Algeria., AbdulMalek A; Cardiology Department, Mustapha Hospital, COCRG Laboratory University Benyoucef Benkhedda, Algiers, Algeria., Alsagheer NK; Althawra Modern General Hospital, Sana'a, Yemen., Dada S; Hammoud University Medical Center, Saida, Lebanon., Mokhtar Z; King Saud Hospital, Unizah, Qaseem, Saudi Arabia., Ali M; Saudi Heart Association, Riyadh, Saudi Arabia., Ullah A; Department of Cardiac Sciences, King Fahad Cardiac Center, College of Medicine, King Saud Medical City, King Saud University, Riyadh, Saudi Arabia.; National Heart and Lung Institute, Imperial College London, London, United Kingdom., AlBackr H; Department of Cardiac Sciences, King Fahad Cardiac Center, College of Medicine, King Saud Medical City, King Saud University, Riyadh, Saudi Arabia., Alhabib KF; Department of Cardiac Sciences, King Fahad Cardiac Center, College of Medicine, King Saud Medical City, King Saud University, Riyadh, Saudi Arabia.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2024 Jan 11; Vol. 19 (1), pp. e0296056. Date of Electronic Publication: 2024 Jan 11 (Print Publication: 2024).
DOI: 10.1371/journal.pone.0296056
Abstrakt: Background: The Program for the Evaluation and Management of Cardiac Events in the Middle East and North Africa (PEACE MENA) is a prospective registry program in Arabian countries that involves in patients with acute myocardial infarction (AMI) or acute heart failure (AHF).
Methods: This prospective, multi-center, multi-country study is the first report of the baseline characteristics and outcomes of inpatients with AMI who were enrolled during the first 14-month recruitment phase. We report the clinical characteristics, socioeconomic, educational levels, and management, in-hospital, one month and one-year outcomes.
Results: Between April 2019 and June 2020, 1377 patients with AMI were enrolled (79.1% males) from 16 Arabian countries. The mean age (± SD) was 58 ± 12 years. Almost half of the population had a net income < $500/month, and 40% had limited education. Nearly half of the cohort had a history of diabetes mellitus, hypertension, or hypercholesterolemia; 53% had STEMI, and almost half (49.7%) underwent a primary percutaneous intervention (PCI) (lowest 4.5% and highest 100%). Thrombolytics were used by 36.2%. (Lowest 6.45% and highest (90.9%). No reperfusion occurred in 13.8% of patients (lowest was 0% and highest 72.7%).Primary PCI was performed less frequently in the lower income group vs. high income group (26.3% vs. 54.7%; P<0.001). Recurrent ischemia occurred more frequently in the low-income group (10.9% vs. 7%; P = 0.018). Re-admission occurred in 9% at 1 month and 30% at 1 year, whereas 1-month mortality was 0.7% and 1-year mortality 4.7%.
Conclusion: In the MENA region, patients with AMI present at a young age and have a high burden of cardiac risk factors. Most of the patients in the registry have a low income and low educational status. There is heterogeneity among key performance indicators of AMI management among various Arabian countries.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2024 Al Saleh et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze: MEDLINE
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