First serological diagnosis of Mycobacterium avium subsp. paratuberculosis infection in sheep in the state of Pernambuco, Brazil.

Autor: de Noronha Xavier A; Department of Veterinary Medicine, Federal Rural University of Pernambuco, Rua Dom Manuel de Medeiros, s/n- Dois Irmãos, Recife, PE, 52171-900, Brazil. amandadenoronha@gmail.com., de Sá LMN; Federal Institute of the Pernambuco Sertão, Floresta Campus, Rua Projetada, s/n - Caetano II, Floresta, PE, 56400-000, Brazil., de Nazaré Santos Ferreira M; Department of Veterinary Medicine, Federal Rural University of Pernambuco, Rua Dom Manuel de Medeiros, s/n- Dois Irmãos, Recife, PE, 52171-900, Brazil., de Oliveira PRF; Department of Veterinary Medicine, Federal Rural University of Pernambuco, Rua Dom Manuel de Medeiros, s/n- Dois Irmãos, Recife, PE, 52171-900, Brazil., de Moraes Peixoto R; Federal Institute of the Pernambuco Sertão, Campus Petrolina - Rural Zone, PE 647, Km 22, PISNC N - 4, Zona Rural, Petrolina, PE, 56302-970, Brazil., Mota RA; Department of Veterinary Medicine, Federal Rural University of Pernambuco, Rua Dom Manuel de Medeiros, s/n- Dois Irmãos, Recife, PE, 52171-900, Brazil., Junior JWP; Department of Veterinary Medicine, Federal Rural University of Pernambuco, Rua Dom Manuel de Medeiros, s/n- Dois Irmãos, Recife, PE, 52171-900, Brazil.
Jazyk: angličtina
Zdroj: Veterinary research communications [Vet Res Commun] 2024 Apr; Vol. 48 (2), pp. 1293-1299. Date of Electronic Publication: 2024 Jan 11.
DOI: 10.1007/s11259-024-10300-8
Abstrakt: This study aimed to diagnose Mycobacterium avium subsp. paratuberculosis (MAP) infections in sheep in the state of Pernambuco, Brazil. A total of 276 blood samples were analyzed using the enzyme-linked immunosorbent assay IDEXX Paratuberculosis Screening kit, and 261 fecal samples were submitted for bacterial culture and polymerase chain reaction tests. An animal-level sero-frequency of 0.72% (n = 2/276) and a farm-level sero-frequency of 20% (n = 2/10) were found. All fecal sample cultures were negative, and molecular analyses were also negative. To the best of our knowledge, this is the first study of MAP infection in sheep in the state of Pernambuco and one of the pioneers in the country. It is an asymptomatic disease that is difficult to diagnose in this species because the susceptibility of sheep to the organism is lower than that of other ruminant species. However, the sero-frequency found reveals that there is MAP exposure in sheep flocks in the region. In addition, serological monitoring can contribute to the observation of the organism's behavior in herds. Our results support the potential risk of MAP infection in sheep in the state of Pernambuco, Brazil.
(© 2024. The Author(s), under exclusive licence to Springer Nature B.V.)
Databáze: MEDLINE
Externí odkaz: