A Systematic Review of COVID-19 Vaccine-Induced Takotsubo Cardiomyopathy: A 2023 Update.

Autor:	Singh B; Medicine, Mayo Hospital, Lahore, PAK., Manita B; Internal Medicine, Ghulam Muhammad Mahar Medical College, Sukkur, PAK., Suman F; Internal Medicine, Ghulam Muhammad Mahar Medical College, Sukkur, PAK., Kumari N; Internal Medicine, Ghulam Muhammad Mahar Medical College, Sukkur, PAK., Shiza ST; Internal Medicine, NYC Health and Hospitals-Lincoln Hospital, New York, USA., Samreen I; Medicine, Deccan College of Medical Sciences, Hyderabad, IND., Shah S; Medicine and Surgery, Hinduhridaysamrat Balasaheb Thackeray (HBT) Medical College and Dr. RN (Rustom Narsi) Cooper Municipal General Hospital, Mumbai, IND., Mokhtar SM; Research, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA., Patel U; Internal Medicine, Medical College Baroda and SSG (Sir Sayajirao General) Hospital, Vadodara, IND., Devi J; Pharmacy, Clifton Medical Services, Karachi, PAK., Reza RR; Internal Medicine, Jalalabad Ragib Rabeya Medical College, Sylhet, BGD., Mohamed KH; Neurology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, GBR., Ahmad S; Internal Medicine, Saint James School of Medicine, Chicago, USA., Nasir H; Internal Medicine, Mayo Hospital, Lahore, PAK.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2023 Dec 11; Vol. 15 (12), pp. e50319. Date of Electronic Publication: 2023 Dec 11 (Print Publication: 2023).
DOI:	10.7759/cureus.50319
Abstrakt:	Takotsubo cardiomyopathy (TCM) is a life-threatening transient left ventricular dysfunction triggered by either physical or emotional stressors. Concerns have been raised on reports of TCM after the coronavirus disease 2019 (COVID-19) vaccine. Our study provides comprehensive detail on COVID-19 vaccine-induced TCM. We conducted a systemic literature search using major databases, including PubMed, EMBASE, and Google Scholar up to November 2023, to identify cases of COVID-19 vaccine-induced TCM using the MeSH terms and keywords "covid-19 vaccines" and "takotsubo cardiomyopathy". We identified 15 case reports, including 16 patients with COVID-19 vaccine-induced TCM. The mean age was 55.81 ± 19.13 years, and 75% of the patients were female. The most common presentation was chest pain (62.5%), and the average time to first symptom onset was 3.12 ± 2.24 days. COVID-19 vaccine-induced TCM was reported in 43.75% of patients receiving the first and second dose each, and 87% of patients had messenger ribonucleic acid (mRNA) COVID-19 vaccine (Pfizer, Moderna). The elevated level of cardiac troponins was found in all the patients with a left ventricular ejection fraction (LVEF) of <50% in 15 patients, and T-wave inversion (50%) was the most common electrocardiographic finding. The mean length of the hospital stay was 7.27 ± 3.95 days, and 87% of patients were discharged. COVID-19 vaccine-induced TCM is a rare but life-threatening complication. TCM should be included in the differential diagnosis of chest pain or dyspnea in patients recently receiving the COVID-19 vaccine. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Singh et al.)
Databáze:	MEDLINE
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