Prognostic Value of Baseline Echocardiographic Parameters in Heart Failure With Improved vs Nonrecovered Ejection Fraction.

Autor: Prana Jagannatha GN; Faculty of Medicine, Udayana University/Prof. dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali, Indonesia.; Department of Cardiology and Vascular Medicine, Faculty of Medicine, Udayana University, Udayana University Hospital, Denpasar, Bali, Indonesia., Suastika LOS; Department of Cardiology and Vascular Medicine, Faculty of Medicine, Udayana University, Udayana University Hospital, Denpasar, Bali, Indonesia., Kosasih AM; Faculty of Medicine, Udayana University/Prof. dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali, Indonesia., de Liyis BG; Faculty of Medicine, Udayana University/Prof. dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali, Indonesia., Yusrika MU; Faculty of Medicine, Udayana University/Prof. dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali, Indonesia., Kamardi S; Faculty of Medicine, Udayana University/Prof. dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali, Indonesia., Adrian J; Faculty of Medicine, Udayana University/Prof. dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali, Indonesia., Pradnyana IWAS; Faculty of Medicine, Udayana University/Prof. dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali, Indonesia., Alamsyah AH; Faculty of Medicine, Udayana University/Prof. dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali, Indonesia., Cardia YMP; Faculty of Medicine, Udayana University/Prof. dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali, Indonesia., Darmawan R; Faculty of Medicine, Udayana University/Prof. dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali, Indonesia., Rumangu AV; Nanjing Medical University, Nanjing, Jiangsu, China., Pertiwi PFK; Faculty of Medicine, Udayana University/Prof. dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali, Indonesia.
Jazyk: angličtina
Zdroj: CJC open [CJC Open] 2023 Aug 23; Vol. 5 (12), pp. 859-869. Date of Electronic Publication: 2023 Aug 23 (Print Publication: 2023).
DOI: 10.1016/j.cjco.2023.08.006
Abstrakt: Background: Ejection fraction (EF) is often used as a prognostic indicator and for classifying heart failure (HF) patients. This study evaluates the association of echocardiographic parameters with HF with improved EF (HFimpEF).
Methods: This single-centre study retrospectively included patients with HF with reduced EF (HFrEF) from a cohort of admitted patients over 2018-2020, who were then followed up prospectively until 2023. The control group was categorized as patients with non-recovered HFrEF, and the population group was categorized as patients with HFimpEF.
Results: A total of 176 patients with HFrEF were included in the study. Non-ischemic etiology was found to be the most prevalent cause of HFimpEF. The baseline echocardiography examination revealed that the HFimpEF group exhibited significantly higher values for tricuspid annular plane systolic excursion (TAPSE; P < 0.001) and inferior vena cava diameter ( P < 0.001). The non-recovered HFrEF group demonstrated higher baseline left atrial volume index (LAVi) values ( P < 0.001). In multivariate analysis, a higher value of TAPSE (odds ratio 3.071; P  = 0.008) and a lower value of LAVi (odds ratio 2.034; P  = 0.008) were independent echocardiography variables associated with HFimpEF. After a mean follow-up duration of 32.5 ± 9.1 months, the HFimpEF group had higher survival from rehospitalization due to worsening HF and lower all-cause mortality (log rank P < 0.001 and P  = 0.005, respectively).
Conclusions: Higher TAPSE and lower LAVi in baseline were associated with the transition from HFrEF to HFimpEF. The HFimpEF group had better survival compared to those with non-recovered HFrEF.
(© 2023 The Authors.)
Databáze: MEDLINE