Cannabis-induced psychotic disorder with onset during withdrawal: a brief report of emerging evidence.

Autor:	Cohen J; Douglas Mental Health University Institute, McGill University, Montreal, QC, Canada., Petitjean H; Benephyt, Strasbourg, France., Blasco MB; Douglas Mental Health University Institute, McGill University, Montreal, QC, Canada.; Integrated Program in Neuroscience, McGill University, Montreal, QC, Canada., Mizrahi R; Douglas Mental Health University Institute, McGill University, Montreal, QC, Canada.; Department of Psychiatry, McGill University, Montreal, QC, Canada.
Jazyk:	angličtina
Zdroj:	Acta neuropsychiatrica [Acta Neuropsychiatr] 2024 Oct; Vol. 36 (5), pp. 325-329. Date of Electronic Publication: 2024 Jan 11.
DOI:	10.1017/neu.2023.60
Abstrakt:	Objectives: The link between cannabis use and psychotic symptoms or disorders is well known. However, the relation between cannabis withdrawal and psychotic symptoms is less studied. Methods: To our knowledge, this is the first publication of an observational systematic report of cannabis-induced psychotic disorder with onset during withdrawal. Here, we review patients presenting to a major emergency room in Montreal between January 2020 and September 2023 in a context of psychotic symptoms following cannabis cessation. Results: In total, seven male and one female patients presented at the peak of cannabis withdrawal with acute psychotic symptoms, representing less than 1% of all emergency service admissions. Conclusions: We discuss current knowledge regarding the endocannabinoid system and dopamine homeostasis to formulate hypotheses regarding these observations.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu