Reconsidering Routine Repeat Group and Screens During Pregnancy-Personalizing Pregnancy Care.

Autor:	Tran A; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC. Electronic address: ann.tran2@fraserhealth.ca., Clarke G; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC; Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB., Callum JL; Department of Pathology and Molecular Medicine, Kingston Health Sciences Centre, Queen's University, Kingston, ON; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON., Smith G; Department of Obstetrics and Gynaecology, Kingston Health Sciences Centre, Queen's University, Kingston, ON., Somerset D; Department of Obstetrics and Gynecology, University of Calgary, Calgary, AB., Thorne J; Department of Obstetrics and Gynaecology, Women's College Hospital, Sinai Health Systems and University of Toronto, Toronto, ON., Lieberman L; Laboratory Medicine Program, University Health Network, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON.
Jazyk:	angličtina
Zdroj:	Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC [J Obstet Gynaecol Can] 2024 May; Vol. 46 (5), pp. 102351. Date of Electronic Publication: 2024 Jan 08.
DOI:	10.1016/j.jogc.2024.102351
Abstrakt:	The group and screen (G&S) are performed in early pregnancy to identify clinically significant antibodies (CSA) that may necessitate fetal monitoring for hemolysis/anemia or affect RhIg eligibility. Guidelines vary, including differences between RhD-positive and negative patients, but typically, the G&S is repeated at 28 weeks, and sometimes pre-delivery. We reviewed data showing a low risk (0.01%-0.43%) of detecting a new CSA in late gestation (late alloimmunization) and the risk of late alloimmunization causing severe hemolysis/anemia is even lower at <0.01%. Routinely repeating a G&S at 28 weeks and delivery may not be necessary for healthy, low-risk pregnancies. (Copyright © 2024 The Society of Obstetricians and Gynaecologists of Canada/La Société des obstétriciens et gynécologues du Canada. Published by Elsevier Inc. All rights reserved.)
Databáze:	MEDLINE
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