In-vitro effect of a single application of CPP-ACP pastes and different fluoridated solutions on the prevention of dental caries around orthodontic brackets.

Autor:	Leite KLF; Universidade Federal do Rio de Janeiro, Faculdade de Odontologia, Departamento de Odontopediatria e Ortodontia (Rio de Janeiro/RJ, Brazil)., Martins ML; Universidade Federal do Rio de Janeiro, Faculdade de Odontologia, Departamento de Odontopediatria e Ortodontia (Rio de Janeiro/RJ, Brazil)., Monteiro ASN; Universidade Federal do Rio de Janeiro, Faculdade de Odontologia, Departamento de Odontopediatria e Ortodontia (Rio de Janeiro/RJ, Brazil)., Vieira TI; Universidade Federal do Rio de Janeiro, Faculdade de Odontologia, Departamento de Odontopediatria e Ortodontia (Rio de Janeiro/RJ, Brazil)., Alexandria AK; Universidade Federal do Rio de Janeiro, Faculdade de Odontologia, Departamento de Odontopediatria e Ortodontia (Rio de Janeiro/RJ, Brazil)., Rocha GM; Universidade Federal do Rio de Janeiro, Instituto de Biofísica Carlos Chagas Filho (Rio de Janeiro/RJ, Brazil)., Fonseca-Gonçalves A; Universidade Federal do Rio de Janeiro, Faculdade de Odontologia, Departamento de Odontopediatria e Ortodontia (Rio de Janeiro/RJ, Brazil)., Pithon MM; Universidade Estadual do Sudoeste da Bahia, Departamento de Saúde (Jequié/BA, Brazil)., Cavalcanti YW; Universidade Federal da Paraíba, Departamento de Odontologia Clínica e Social (João Pessoa/PB, Brazil)., Maia LC; Universidade Federal do Rio de Janeiro, Faculdade de Odontologia, Departamento de Odontopediatria e Ortodontia (Rio de Janeiro/RJ, Brazil).
Jazyk:	angličtina
Zdroj:	Dental press journal of orthodontics [Dental Press J Orthod] 2024 Jan 08; Vol. 28 (6), pp. e2321383. Date of Electronic Publication: 2024 Jan 08 (Print Publication: 2024).
DOI:	10.1590/2177-6709.28.6.e2321383.oar
Abstrakt:	Objective: To assess the in-vitro effect of single applications of CPP-ACP pastes and different fluoridated solutions on the prevention of dental caries around orthodontic brackets. Material and Methods: Tooth/bracket sets (n=65) were immersed in artificial saliva (1h at 37ºC) and randomly subjected to single applications (100µL; 1min) of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP emulsion), CPP-ACP with fluoride (CPP-ACPF emulsion), solutions of titanium tetrafluoride (TiF4) or sodium fluoride (NaF), or no treatment (CG). Multispecies biofilm (5 x 105 CFU/mL) was formed in the presence of 2% sucrose. After 24 h, the pH and the concentration of total soluble fluoride (TSF) were analyzed by culture medium. The presence of active white spot lesions (WSL) evaluated by macroscopic examination and the percent surface mineral loss (%SML) were analyzed. Also, the topography of enamel was detected by analysis of scanning electron microscopy (SEM). The data was assessed by chi-square, Kruskal-Wallis, and Mann-Whitney tests (p < 0.05). Results: Fluoride-containing compounds led to a smaller pH reduction than did CPP-ACP and CG (p<0.05). There was difference in TSF between the groups (p<0.05), denoted as TiF4> NaF > CPP-ACPF > CPP-ACP > CG. Regarding the presence of WSL and %SML, the NaF group obtained lower values (p<0.05), while TiF4 and CPP-ACPF were similar (p>0.05). SEM demonstrated that fluoride-free groups had a larger surface dissolution. Conclusion: Fluoridated groups including solutions and CPP-ACPF were more effective than CPP-ACP in reducing enamel demineralization around orthodontic brackets after a single application.
Databáze:	MEDLINE
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