Atrial Fibrillation Ablation in Congenital Heart Disease: Therapeutic Challenges and Future Perspectives.

Autor: Baroutidou A; First Department of Cardiology AHEPA University Hospital, Aristotle University of Thessaloniki Thessaloniki Greece., Otountzidis N; First Department of Cardiology AHEPA University Hospital, Aristotle University of Thessaloniki Thessaloniki Greece., Papazoglou AS; Athens Naval Hospital Athens Greece., Moysidis DV; 424 General Military Hospital Thessaloniki Greece., Kartas A; First Department of Cardiology AHEPA University Hospital, Aristotle University of Thessaloniki Thessaloniki Greece., Mantziari L; Interbalkan Medical Center Thessaloniki Greece., Kamperidis V; First Department of Cardiology AHEPA University Hospital, Aristotle University of Thessaloniki Thessaloniki Greece., Ziakas A; First Department of Cardiology AHEPA University Hospital, Aristotle University of Thessaloniki Thessaloniki Greece., Giannakoulas G; First Department of Cardiology AHEPA University Hospital, Aristotle University of Thessaloniki Thessaloniki Greece.
Jazyk: angličtina
Zdroj: Journal of the American Heart Association [J Am Heart Assoc] 2024 Jan 16; Vol. 13 (2), pp. e032102. Date of Electronic Publication: 2024 Jan 09.
DOI: 10.1161/JAHA.123.032102
Abstrakt: The increasing prevalence of atrial fibrillation (AF) in adults with congenital heart disease raises significant questions regarding its management. The unique underlying anatomic and physiological background further adds to the difficulty in eliminating the AF burden in these patients. Herein, we provide an overview of the current knowledge on the pathophysiology and risk factors for AF in adult congenital heart disease, with a special focus on the existing challenges in AF ablation. Emerging imaging modalities and ablation techniques might have a role to play. Evidence regarding the safety and efficacy of AF ablation in adult congenital heart disease is summarized, especially for patients with an atrial septal defect, Ebstein anomaly of the tricuspid valve, tetralogy of Fallot, and Fontan circulation. Finally, any remaining gaps in knowledge and potential areas of future research are highlighted.
Databáze: MEDLINE