Female Genital Schistosomiasis Lesion Resolution Post-Treatment with Praziquantel in Zambian Adults.

Autor: Kabengele C; Center for Family Health Research Zambia, Lusaka, Zambia., Mwangelwa S; Center for Family Health Research Zambia, Ndola, Zambia., Kilembe W; Center for Family Health Research Zambia, Lusaka, Zambia., Vwalika B; Center for Family Health Research Zambia, Lusaka, Zambia., Inambao M; Center for Family Health Research Zambia, Ndola, Zambia., Moonga V; Center for Family Health Research Zambia, Lusaka, Zambia., Himukumbwa C; Center for Family Health Research Zambia, Ndola, Zambia., Secor WE; Centers for Disease Control and Prevention, Atlanta, Georgia., Parker R; Rwanda Zambia HIV Research Group, Department of Pathology & Laboratory Medicine, School of Medicine and Hubert Department of Global Health, Rollins School of Public Health, Laney Graduate School, Emory University, Atlanta, Georgia., Tichacek A; Rwanda Zambia HIV Research Group, Department of Pathology & Laboratory Medicine, School of Medicine and Hubert Department of Global Health, Rollins School of Public Health, Laney Graduate School, Emory University, Atlanta, Georgia., Bustinduy AL; Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, United Kingdom., Allen S; Rwanda Zambia HIV Research Group, Department of Pathology & Laboratory Medicine, School of Medicine and Hubert Department of Global Health, Rollins School of Public Health, Laney Graduate School, Emory University, Atlanta, Georgia., Wall KM; Rwanda Zambia HIV Research Group, Department of Pathology & Laboratory Medicine, School of Medicine and Hubert Department of Global Health, Rollins School of Public Health, Laney Graduate School, Emory University, Atlanta, Georgia.
Jazyk: angličtina
Zdroj: The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2024 Jan 09; Vol. 110 (2), pp. 250-253. Date of Electronic Publication: 2024 Jan 09 (Print Publication: 2024).
DOI: 10.4269/ajtmh.23-0552
Abstrakt: We evaluated changes in female genital schistosomiasis (FGS) 6 to 12 months after praziquantel treatment among 43 adult Zambian women. Most women (60%) experienced decreased FGS severity and 23% experienced complete lesion resolution. This is the first study to demonstrate a meaningful effect of praziquantel treatment of FGS in adult women.
Databáze: MEDLINE