Anterior plaque brachytherapy placement for treatment of iris and iridociliary melanomas - Surgical procedure and institutional experience.

Autor: Pike S; USC Roski Eye Institute, Keck School of Medicine of USC, Los Angeles, CA, USA.; The Vision Center, Children's Hospital Los Angeles, Los Angeles, CA, USA., Engelhard SB; USC Roski Eye Institute, Keck School of Medicine of USC, Los Angeles, CA, USA.; The Vision Center, Children's Hospital Los Angeles, Los Angeles, CA, USA., Greig LC; USC Roski Eye Institute, Keck School of Medicine of USC, Los Angeles, CA, USA.; The Vision Center, Children's Hospital Los Angeles, Los Angeles, CA, USA., Woods K; Radiation Oncology, Keck School of Medicine of USC, Los Angeles, CA, USA., Jennelle RL; Radiation Oncology, Keck School of Medicine of USC, Los Angeles, CA, USA., Berry JL; USC Roski Eye Institute, Keck School of Medicine of USC, Los Angeles, CA, USA.; The Vision Center, Children's Hospital Los Angeles, Los Angeles, CA, USA.; Radiation Oncology, Keck School of Medicine of USC, Los Angeles, CA, USA.
Jazyk: angličtina
Zdroj: Indian journal of ophthalmology [Indian J Ophthalmol] 2024 Jun 01; Vol. 72 (6), pp. 912-915. Date of Electronic Publication: 2024 Jan 08.
DOI: 10.4103/IJO.IJO_824_23
Abstrakt: Surgical placement of eye plaque brachytherapy (EPB) is the standard of care for the treatment of uveal melanomas, including iris/iridociliary melanomas. However, unique challenges exist in anterior EPB placement. Here, we describe a surgical technique for anterior EPB placement when placement requires plaque positioning onto the cornea. Blunt conjunctival peritomy exposes the sclera overlying the tumor. A "dummy" plaque is placed, with positioning confirmed by direct visualization. The amniotic membrane is draped across the cornea and anchored with the eyelet sutures, the plaque is placed overlying the membrane, the conjunctiva is closed over the plaque, and a temporary tarsorrhaphy is performed. One week later, the conjunctival incision is reopened for plaque/amniotic membrane removal. This technique was employed in the treatment of 12 iris/iridociliary melanomas at our institution, with no instances of corneal damage. In placing an anterior plaque, employing this technique allows appropriate cancer treatment while optimizing patient comfort and corneal integrity.
(Copyright © 2024 Copyright: © 2024 Indian Journal of Ophthalmology.)
Databáze: MEDLINE
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