Indwelling central venous catheter infection with Chryseobacterium shandongense - successful eradication in a 5-year-old with cystic fibrosis.

Autor:	Rowan A; Department of Paediatrics, University Hospital Limerick, Dooradoyle, Limerick, Ireland., Verbruggen TF; Department of Paediatrics, University Hospital Limerick, Dooradoyle, Limerick, Ireland., O'Connell NH; Department of Microbiology, University Hospital Limerick, Dooradoyle, Limerick, Ireland.; School of Medicine and Centre for Interventions in Infection, Inflammation and Immunity (4i), University of Limerick, Limerick, Ireland., Stapleton PJ; Department of Microbiology, University Hospital Limerick, Dooradoyle, Limerick, Ireland., Dunne CP; School of Medicine and Centre for Interventions in Infection, Inflammation and Immunity (4i), University of Limerick, Limerick, Ireland., Linnane B; Department of Paediatrics, University Hospital Limerick, Dooradoyle, Limerick, Ireland.; School of Medicine and Centre for Interventions in Infection, Inflammation and Immunity (4i), University of Limerick, Limerick, Ireland., Butler D; Department of Paediatrics, University Hospital Limerick, Dooradoyle, Limerick, Ireland.
Jazyk:	angličtina
Zdroj:	Access microbiology [Access Microbiol] 2023 Dec 05; Vol. 5 (12). Date of Electronic Publication: 2023 Dec 05 (Print Publication: 2023).
DOI:	10.1099/acmi.0.000700.v3
Abstrakt:	Introduction: Chryseobacterium shandongense is a Gram-negative Flavobacterium bacillus with intrinsic multidrug-resistant properties. Case Presentation: Herein, we present the first case report of human C. shandongense infection, relating to an implantable portal and catheter (port-a-cath) central line in a 5-year-old female with cystic fibrosis. The infection was identified using a Bruker MALDI-TOF Biotyper with BDAL (v12) of blood, which was cultured due to pyrexia and rigour following port-a-cath access. This report details the effective eradication of C. shandongense infection from the port-a-cath device using initial empirical gentamicin followed by targeted ciprofloxacin locks and systemic antibiotics. Conclusion: We demonstrated successful eradication of C. shandongense from a port-a-cath device, including the minimum inhibitory concentrations (MICs) required in this case. The result was eradication of central access infection, preventing progression to bacteraemia/septicaemia and preserving central access in a child with cystic fibrosis and established respiratory disease. Competing Interests: The authors declare that there are no conflicts of interest. (© 2023 The Authors.)
Databáze:	MEDLINE
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