Efficacy of an oscillating positive expiratory pressure device in patients with Mycobacterium avium complex pulmonary disease.

Autor: Kurahara Y; Department of Internal Medicine, National Hospital Organization Kinki-Chuo Chest Medical Center, Osaka, Japan; Department of Infectious Diseases, National Hospital Organization Kinki-Chuo Chest Medical Center, Osaka, Japan; Clinical Research Center, National Hospital Organization Kinki-Chuo Chest Medical Center, Osaka, Japan., Tanaka Y; Department of Internal Medicine, National Hospital Organization Kinki-Chuo Chest Medical Center, Osaka, Japan; Department of Infectious Diseases, National Hospital Organization Kinki-Chuo Chest Medical Center, Osaka, Japan., Kobayashi T; Clinical Research Center, National Hospital Organization Kinki-Chuo Chest Medical Center, Osaka, Japan., Yoshida S; Clinical Research Center, National Hospital Organization Kinki-Chuo Chest Medical Center, Osaka, Japan., Tsuyuguchi K; Department of Internal Medicine, National Hospital Organization Kinki-Chuo Chest Medical Center, Osaka, Japan; Department of Infectious Diseases, National Hospital Organization Kinki-Chuo Chest Medical Center, Osaka, Japan; Clinical Research Center, National Hospital Organization Kinki-Chuo Chest Medical Center, Osaka, Japan. Electronic address: tsuyuguchi.kazunari.ky@mail.hosp.go.jp.
Jazyk: angličtina
Zdroj: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy [J Infect Chemother] 2024 Aug; Vol. 30 (8), pp. 780-784. Date of Electronic Publication: 2024 Jan 03.
DOI: 10.1016/j.jiac.2024.01.001
Abstrakt: Patients with Mycobacterium avium complex pulmonary disease (MAC-PD) often suffer from chronic symptoms such as sputum production, which reduces quality of life. Oscillatory positive expiratory pressure (OPEP) devices are used in physiotherapy to promote the clearance of respiratory secretions. We report two cases of improved lung function and improved scores on the Leicester Cough Questionnaire (LCQ) and the Breathlessness, Cough and Sputum Scale (BCSS) after the use of OPEP in patients with MAC-PD where treatment with guideline-based therapy, including amikacin liposome inhalation suspension, had proved ineffective for symptoms. Use of OPEP might maximize the efficacy of therapy and thereby improves outcomes in patients with MAC-PD. It is important to use both guideline-based therapy and OPEP, especially in patients whose health-related quality of life is affected by sputum symptoms. Further prospective studies are warranted to assess the benefit of adding OPEP to guidelines concerning therapy for patients with MAC-PD and sputum symptoms.
Competing Interests: Declarations of competing interest None.
(Copyright © 2024 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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