Assessing medication adherence and their associated factors amongst type-2 diabetes mellitus patients of Jazan Province, Saudi Arabia: A single-center, cross-sectional study.

Autor:	Khardali A; Pharmacy Practice Research Unit, College of Pharmacy, Jazan University, Jizan - 45142, Jazan, Saudi Arabia.; Department of Clinical Pharmacy, College of Pharmacy, Jazan University, Jizan - 45142, Jazan, Saudi Arabia., Kashan Syed N; Pharmacy Practice Research Unit, College of Pharmacy, Jazan University, Jizan - 45142, Jazan, Saudi Arabia.; Department of Clinical Pharmacy, College of Pharmacy, Jazan University, Jizan - 45142, Jazan, Saudi Arabia., Alqahtani SS; Department of Clinical Pharmacy, College of Pharmacy, King Khalid University, Abha, Saudi Arabia., Qadri M; Department of Pharmacology and Toxicology, College of Pharmacy, Jazan University, Jazan-45142, Saudi Arabia.; Inflammation Pharmacology and Drug Discovery Unit, Medical Research Center, Jazan University, Jazan-45142, Saudi Arabia., Meraya AM; Pharmacy Practice Research Unit, College of Pharmacy, Jazan University, Jizan - 45142, Jazan, Saudi Arabia.; Department of Clinical Pharmacy, College of Pharmacy, Jazan University, Jizan - 45142, Jazan, Saudi Arabia., Rajeh N; Jazan Endocrinology and Diabetes Centre, Jizan - 82723, Jazan, Saudi Arabia., Aqeely F; Jazan Endocrinology and Diabetes Centre, Jizan - 82723, Jazan, Saudi Arabia., Alrajhi S; College of Pharmacy, Jazan University, Jizan - 45142, Saudi Arabia., Zanoom A; College of Pharmacy, Jazan University, Jizan - 45142, Saudi Arabia., Gunfuthi S; College of Pharmacy, Jazan University, Jizan - 45142, Saudi Arabia., Basudan W; College of Pharmacy, Jazan University, Jizan - 45142, Saudi Arabia., Hakami TK; Faculty of Medicine, Jazan University, Jazan 45142, Saudi Arabia., Abdelgadir MA; Pharmacy Practice Research Unit, College of Pharmacy, Jazan University, Jizan - 45142, Jazan, Saudi Arabia.; Department of Clinical Pharmacy, College of Pharmacy, Jazan University, Jizan - 45142, Jazan, Saudi Arabia.
Jazyk:	angličtina
Zdroj:	Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society [Saudi Pharm J] 2024 Jan; Vol. 32 (1), pp. 101896. Date of Electronic Publication: 2023 Dec 06.
DOI:	10.1016/j.jsps.2023.101896
Abstrakt:	Background: The prevalence of type 2 diabetes mellitus (T2DM) globally is reaching epidemic proportions. By 2035, it is projected to increase to 417 million, which is of significant concern as T2DM represents the most oversized budget item in many healthcare systems, primarily due to the high rates of morbidity and mortality associated with the disease. The worldwide cost burden of T2DM has been inexorably growing. A key contributor to the remarkably high morbidity and mortality rates is poor glycemic control potentially associated with medication non-adherence. Aim: The present research's main objective included assessing medication adherence among patients with T2DM in a single center in Jazan Province. Methods: Three hundred nine patients with T2DM participated in a cross-sectional survey over three months (September to November 2022). The study participants comprised 50.8 % (females) and 49.2 % (males), with a mean age of 44.12 years (SD ± 12.70). A 31-item self-report questionnaire was used for data collection. Results: Sixty-six percent of the sample were found to be adherent to their T2DM therapy. A positive association was noticed between the GMAS score and the participant's age (r = 0.24; p < 0.01). The participants' medication adherence was significantly associated with having age above 50 years ( χ ² = 13.62; p = 0.001), residing in urban localities ( χ ² = 21.37 ; p < 0.001 ), being married ( χ ² = 12.80 ; p = 0.002), having glycated hemoglobin level more than 8 % ( χ ² = 6.99 ; p = 0.03 ) and taking between one to three medications per day ( χ ² = 17.63 ; p < 0.001 ). Conclusion: The majority of T2DM patients in the present study were found adherent to their anti-diabetic medications, particularly older patients. Future studies should focus on exploring the reasons for the reported high adherence among older patients and non-adherence among younger patients, as this could facilitate the development of a strategy to enhance adherence. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (© 2023 The Authors.)
Databáze:	MEDLINE
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