Different effects of CO 2 laser and estrogen treatment on vaginal mucosa microbiota and function in genitourinary syndrome of menopause patients.
Autor: | Qi Y; Department of Obstetrics and Gynecology, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., Mo K; Department of Obstetrics and Gynecology, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., Wang A; Department of Obstetrics and Gynecology, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, China., He Y; Department of Obstetrics and Gynecology, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. |
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Jazyk: | angličtina |
Zdroj: | The journal of obstetrics and gynaecology research [J Obstet Gynaecol Res] 2024 Apr; Vol. 50 (4), pp. 671-681. Date of Electronic Publication: 2024 Jan 04. |
DOI: | 10.1111/jog.15876 |
Abstrakt: | Aim: To characterize the effects of CO Methods: Sixty-four patients with genitourinary syndrome were divided into the estrogen group, the CO Results: The results showed that both treatments reduced alpha diversity in the vaginal flora. Additionally, the abundance of 65 genera differed significantly between the treatment and control groups, with an increase in potentially beneficial bacteria such as Lactobacillus, IheB3_7, Mycoplasma urealyticum, and Streptococcus. In addition, the VHI and UDI-6 scores improved in both treatment groups compared to the control group after 3 months. Whereas VHI and UDI-6 scores were close to baseline in the estrogen group, and remained significantly improved in the CO Conclusions: Both CO (© 2024 The Authors. Journal of Obstetrics and Gynaecology Research published by John Wiley & Sons Australia, Ltd on behalf of Japan Society of Obstetrics and Gynecology.) |
Databáze: | MEDLINE |
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