[Interdisciplinary diagnostics and therapy of malignant mesothelioma].

Autor: van der Linde LIS; Zytopathologie, Institut für Pathologie Universität Hamburg, Hamburg, Deutschland., Hantzsch-Kuhn B; Onkologie, LungenClinic Grosshansdorf GmbH, Grosshansdorf, Deutschland., Ellebrecht D; Onkologie, LungenClinic Grosshansdorf GmbH, Grosshansdorf, Deutschland., Stellmacher F; Hämatopathologie, Institut für Hämatopathologie, Hamburg, Deutschland., Welker L; Zytopathologie, Institut für Pathologie Universität Hamburg, Hamburg, Deutschland.
Jazyk: němčina
Zdroj: Pneumologie (Stuttgart, Germany) [Pneumologie] 2024 Apr; Vol. 78 (4), pp. 262-268. Date of Electronic Publication: 2024 Jan 04.
DOI: 10.1055/a-2202-5445
Abstrakt: The asbestos-related malignant mesothelioma (MM) is one of the common occupational cancers in Germany with approximately 1000 new cases per year. Provided that the appropriate diagnostic criteria are fulfilled, MM can be diagnosed with high specificity from both histological and cytological specimens. However, many MM are detected cyto-/histologically only at advanced stages. Clinical/radiological aspects complement each other and enable interdisciplinary assessment of tumor stage and individualized decisions on the best possible therapeutic options. Diagnostically, video-assisted thoracoscopy (VATS) has the highest priority. Therapy planning is based on the MM subtype, tumor spread and stage, and the patient's clinical condition. MM has generally a very unfavorable prognosis. Accordingly, the standard therapy aims at a macroscopic radical tumor resection in terms of cytoreduction within the framework of a suitable multimodal therapy concept (chemotherapy, radiotherapy, psychooncology). The aim of palliative measures should be primarily symptom control. Overall, interdisciplinary diagnosis and therapy of MM is crucial for the best possible care of MM patients.
Competing Interests: Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht.
(Thieme. All rights reserved.)
Databáze: MEDLINE