[Seizures in pregnancy: not always eclamptic seizures].

Autor:	Cohen ES; Zaans Medisch Centrum, afd. Verloskunde en Gynaecologie,Zaandam., Hooker AB; Zaans Medisch Centrum, afd. Verloskunde en Gynaecologie, Zaandam.; Contact: Angelo B. Hooker (hooker.A@zaansmc.nl)., Wiendels NJ; Zaans Medisch Centrum, afd. Neurologie, Zaandam., Abdolrahimi Raeni R; Zaans Medisch Centrum, afd. Spoedeisende Hulp, Zaandam., Verburg N; Amsterdam UMC, afd. Neurochirurgie, Amsterdam.
Jazyk:	Dutch; Flemish
Zdroj:	Nederlands tijdschrift voor geneeskunde [Ned Tijdschr Geneeskd] 2023 Nov 27; Vol. 167. Date of Electronic Publication: 2023 Nov 27.
Abstrakt:	Background: The differential diagnosis of seizures during pregnancy is extensive and includes potentially fatal underlying diagnoses. Both pregnancy and non-pregnancy related aetiologies should be considered. Case Description: A 38-years old pregnant woman presented to the emergency department at 31 weeks and 5 days with generalized tonic-clonic seizures. Initial an eclamptic seizure was suspected. Because the seizures lasted despite treatment with magnesium sulphate and anti-epileptic medication. Imaging of the head was performed and a brain tumour was suspected and a biopsy revealed the presence of a high-grade glioma. At 37 weeks of gestation, labour was induced and the patient delivered a healthy daughter. The patient was then palliatively treated with antiepileptic drugs and chemotherapy. Conclusion: Structural brain changes caused by a high-grade gliomas represent a rare cause of seizure during pregnancy, emphasizing the importance of considering non-obstetric causes of seizures in pregnant women.
Databáze:	MEDLINE
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