Impact of COVID-19 infection on patients admitted with nonvariceal upper gastrointestinal bleeding: an analysis from the National Inpatient Sample.

Autor: Elfert K; Department of Internal Medicine, SBH Health System, New York, New York, USA., Malik M; Department of Internal Medicine, SBH Health System, New York, New York, USA., Aboursheid T; Department of Internal Medicine, Ascension Saint Francis Hospital, Evanston, Illinois, USA., Mohamed M; Department of Internal Medicine, Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA., Elfert Y; Department of Pediatrics, UH Cleveland Medical Center, Cleveland, Ohio, USA., Beran A; Division of Gastroenterology and Hepatology, Indiana University, Indianapolis, Indiana, USA., Jaber F; Department of Internal Medicine, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri, USA., Elromisy E; Tanta University Faculty of Medicine, Tanta, Gharbiyah, Egypt., Al-Taee A; Carle Illinois College of Medicine, University of Illinois Urbana-Champaign, Urbana, Illinois, USA., Kahaleh M; Division of Gastroenterology, Department of Medicine, Robert Wood Johnson University Hospital, New Brunswick, New Jersey, USA.
Jazyk: angličtina
Zdroj: Proceedings (Baylor University. Medical Center) [Proc (Bayl Univ Med Cent)] 2023 Dec 20; Vol. 37 (1), pp. 36-41. Date of Electronic Publication: 2023 Dec 20 (Print Publication: 2024).
DOI: 10.1080/08998280.2023.2260280
Abstrakt: Background: Nonvariceal upper gastrointestinal bleeding (NVUGIB) is a medical emergency that has significant morbidity and mortality. The available data about the impact of COVID-19 infection on mortality in patients with NVUGIB is limited.
Methods: We identified all hospitalizations with a principal diagnosis of NVUGIB in 2020. The baseline characteristics and clinical outcomes of patients with COVID-19 infection were compared to those without COVID-19 infection.
Results: NVUGIB patients with COVID-19 infection had higher mortality (5% vs 2%, P  < 0.0001), a longer mean length of stay (6.85 vs 4.48 days, P  < 0.0001), and a lower rate of esophagogastroduodenoscopy utilization (40% vs 51%, P  < 0.0001) than those without COVID-19 infection. Multivariate logistic regression analysis showed that COVID-19 infection was associated with a higher mortality rate (odds ratio 2.2, 95% confidence interval, 1.4-3.4).
Conclusions: COVID-19 infection is an independent predictor of mortality in adults hospitalized with NVUGIB.
Competing Interests: Khaled Elfert, MD, received a travel grant for the abstract titled “Trends, characteristics, and outcomes of hospitalized patients with primary sclerosing cholangitis in the United States” that was presented at the Digestive Disease Week. Michel Kahaleh, MD, has received grant support from Boston Scientific, Fujinon, Apollo Endosurgery, Cook Endoscopy, Olympus, and MI Tech. He is a consultant for Boston Scientific and ABBvie. None of that funding was related to this paper. The other authors report no funding or potential conflicts of interest.
(Copyright © 2023 Baylor University Medical Center.)
Databáze: MEDLINE