Unusual cutaneous adverse reaction to an erectile dysfunction drug: A case report.

Autor: Soares I; Department of Dermatology, Hospital de Santa Maria, Avenida Professor Egas Moniz MB, 1649-028, Lisboa, Portugal., Amaral IP; Department of Dermatology, Hospital de Santa Maria, Avenida Professor Egas Moniz MB, 1649-028, Lisboa, Portugal., Correia MP; Department of Dermatology, Hospital de Santa Maria, Avenida Professor Egas Moniz MB, 1649-028, Lisboa, Portugal., Filipe P; Department of Dermatology, Hospital de Santa Maria, Avenida Professor Egas Moniz MB, 1649-028, Lisboa, Portugal.; Dermatology Clinic, Faculdade de Medicina da Universidade de Lisboa, Avenida Professor Egas Moniz MB, 1649-028, Lisboa, Portugal.
Jazyk: angličtina
Zdroj: Urology case reports [Urol Case Rep] 2023 Dec 09; Vol. 52, pp. 102637. Date of Electronic Publication: 2023 Dec 09 (Print Publication: 2024).
DOI: 10.1016/j.eucr.2023.102637
Abstrakt: We presents an unique and significant case of Acute Generalized Exanthematous Pustulosis (AGEP) associated with the use of tadalafil, a phosphodiesterase type 5 inhibitor for erectile dysfunction. AGEP, typically linked to antibiotics and antiepileptics, had not been previously reported with tadaladil in the MEDLINE database. The case involved a 40-year-old male who developed an erythematous rash, fever and sterile pustules after starting tadalafil. A skin biopsy confirmed AGEP. Discontinuation of the drug and treatment with prednsiolone cleared the dermatosis. This case emphasizes the need for awareness among healthcare providers regarding this potential adverse reaction, considering the growing use of tadalafil.
Competing Interests: None.
(© 2023 The Authors.)
Databáze: MEDLINE