Challenges and opportunities in the diagnosis and treatment of early-onset psychosis: a case series from the youth affective disorders clinic in Stockholm, Sweden.

Autor: Lundberg M; Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden.; The Affective Disorders Clinic, Child and Adolescent Psychiatry, Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden.; Department of Clinical Science and Education, Södersjukhuset, Internal Medicine, Karolinska Institutet, Stockholm, Sweden., Andersson P; Department of Clinical Neuroscience/Psychology, Karolinska Institutet, Stockholm, Sweden.; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Karolinska University Hospital, SE-171 76, Stockholm, Sweden., Lundberg J; Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden.; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Karolinska University Hospital, SE-171 76, Stockholm, Sweden., Desai Boström AE; Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden. adrian.desai.bostrom@ki.se.; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Karolinska University Hospital, SE-171 76, Stockholm, Sweden. adrian.desai.bostrom@ki.se.; Department of Clinical Sciences/Psychiatry, Umeå University, Umeå, Sweden. adrian.desai.bostrom@ki.se.
Jazyk: angličtina
Zdroj: Schizophrenia (Heidelberg, Germany) [Schizophrenia (Heidelb)] 2024 Jan 03; Vol. 10 (1), pp. 5. Date of Electronic Publication: 2024 Jan 03.
DOI: 10.1038/s41537-023-00427-z
Abstrakt: Early-onset psychosis is linked to adverse long-term outcomes, recurrent disease course, and prolonged periods of untreated illness; thus highlighting the urgency of improving early identification and intervention. This paper discusses three cases where initial emphasis on psychosocial treatments led to diagnostic and therapeutic delays: (1) a 15-year-old misdiagnosed with emotionally unstable personality disorder and autism, who improved on bipolar medication and antipsychotics; (2) another 15-year-old misdiagnosed with autism, who stabilized on lithium and antipsychotics, subsequently allowing for gender dysphoria evaluation; (3) a 9-year-old autistic boy incorrectly treated for ADHD, who recovered with appropriate antipsychotic treatment. These cases illuminate the vital importance of adhering to a diagnostic hierarchy, prioritizing diagnostic utility, and conducting longitudinal evaluations to facilitate early targeted treatment of psychotic symptoms in early-onset psychosis. Adherence to such strategies can minimize delays in managing early-onset psychosis and improve long-term prognoses.
(© 2024. The Author(s).)
Databáze: MEDLINE