International consensus on post-transplantation diabetes mellitus.

Autor:	Sharif A; Department of Nephrology and Transplantation, University Hospitals Birmingham, Birmingham, United Kingdom.; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom., Chakkera H; Division of Nephrology and Hypertension, Mayo Clinic, Scottsdale, AZ, United States of America., de Vries APJ; Leiden Transplant Center, Leiden University Medical Center, Leiden, The Netherlands.; Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands., Eller K; Division of Nephrology, Department of Internal Medicine, Medical University of Graz, Graz Austria., Guthoff M; Department of Diabetology, Endocrinology, Nephrology, University of Tübingen, Tübingen, Germany., Haller MC; Ordensklinikum Linz, Elisabethinen Hospital, Department of Medicine III, Nephrology, Hypertension, Transplantation, Rheumatology, Geriatrics, Linz, Austria.; Medical University of Vienna, CeMSIIS, Section for Clinical Biometrics, Vienna, Austria., Hornum M; Department of Nephrology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark., Nordheim E; Department of Transplantation Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Nydalen, Norway.; Department of Nephrology, Oslo University Hospital-Ullevål, Oslo, Nydalen, Norway., Kautzky-Willer A; Department of Internal Medicine III, Clinical Division of Endocrinology and Metabolism, Medical University of Vienna, Vienna, Austria., Krebs M; Department of Internal Medicine III, Clinical Division of Endocrinology and Metabolism, Medical University of Vienna, Vienna, Austria., Kukla A; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, United States of America.; William J. von Liebig Center for Transplantation and Clinical Regeneration, Mayo Clinic, Rochester, MN, United States of America., Kurnikowski A; Department of Internal Medicine III, Clinical Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria., Schwaiger E; Department of Internal Medicine, Brothers of Saint John of God Eisenstadt, Eisenstadt, Austria., Montero N; Nephrology Department, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, University of Barcelona, Barcelona Spain., Pascual J; Institute Mar for Medical Research-IMIM, Barcelona,  Spain.; Department of Nephrology, Hospital Universitario 12 de Octubre, Madrid, Spain., Jenssen TG; Department of Transplantation Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Nydalen, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Porrini E; Instituto de Tecnologías Biomédicas (ITB), University of La Laguna, Research Unit Department, Hospital Universitario de Canarias, Tenerife, Spain., Hecking M; Department of Internal Medicine III, Clinical Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria.; Center for Public Health, Department of Epidemiology, Medical University of Vienna, Vienna, Austria.; Kuratorium for Dialysis and Kidney Transplantation (KfH), Neu-Isenburg, Germany.
Jazyk:	angličtina
Zdroj:	Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association [Nephrol Dial Transplant] 2024 Feb 28; Vol. 39 (3), pp. 531-549.
DOI:	10.1093/ndt/gfad258
Abstrakt:	Post-transplantation diabetes mellitus (PTDM) remains a leading complication after solid organ transplantation. Previous international PTDM consensus meetings in 2003 and 2013 provided standardized frameworks to reduce heterogeneity in diagnosis, risk stratification and management. However, the last decade has seen significant advancements in our PTDM knowledge complemented by rapidly changing treatment algorithms for management of diabetes in the general population. In view of these developments, and to ensure reduced variation in clinical practice, a 3rd international PTDM Consensus Meeting was planned and held from 6-8 May 2022 in Vienna, Austria involving global delegates with PTDM expertise to update the previous reports. This update includes opinion statements concerning optimal diagnostic tools, recognition of prediabetes (impaired fasting glucose and/or impaired glucose tolerance), new mechanistic insights, immunosuppression modification, evidence-based strategies to prevent PTDM, treatment hierarchy for incorporating novel glucose-lowering agents and suggestions for the future direction of PTDM research to address unmet needs. Due to the paucity of good quality evidence, consensus meeting participants agreed that making GRADE (Grading of Recommendations, Assessment, Development, and Evaluations) recommendations would be flawed. Although kidney-allograft centric, we suggest that these opinion statements can be appraised by the transplantation community for implementation across different solid organ transplant cohorts. Acknowledging the paucity of published literature, this report reflects consensus expert opinion. Attaining evidence is desirable to ensure establishment of optimized care for any solid organ transplant recipient at risk of, or who develops, PTDM as we strive to improve long-term outcomes. (© The Author(s) 2024. Published by Oxford University Press on behalf of the ERA.)
Databáze:	MEDLINE
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