| Autor: |
Klose SM; Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, University of Melbourne, VIC, Australia.; Institute of Molecular Medicine and Experimental Immunology, Faculty of Medicine, University of Bonn, NRW, Germany., Legione AR; Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, University of Melbourne, VIC, Australia., Monotti I; U-Vet, Department of Veterinary Clinical Sciences, Melbourne Veterinary School, University of Melbourne, VIC, Australia., Bushell RN; U-Vet, Department of Veterinary Clinical Sciences, Melbourne Veterinary School, University of Melbourne, VIC, Australia., Sugiyama T; U-Vet, Department of Veterinary Clinical Sciences, Melbourne Veterinary School, University of Melbourne, VIC, Australia.; Present address: Animalius Vet, WA, Australia., Browning GF; Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, University of Melbourne, VIC, Australia., Vaz PK; Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, University of Melbourne, VIC, Australia. |
| Abstrakt: |
A domestic short hair cat ( Felis catus ) suffering from a purulent wound infection resulting from a dog bite was sampled for bacterial culture and isolation as the wound had been unresponsive to prolonged antimicrobial treatment. A mycoplasma was isolated from the wound. Whole genome sequencing of the isolate was performed using short-read Illumina and long-read Oxford Nanopore chemistry, and the organism was identified as Mycoplasma edwardii . Comparison of the genome sequence of the isolate to a reference M. edwardii genome sequence (canid isolate) identified the loss of several key bacterial factors involved in genome editing, as well the insertion of several novel ORFs most closely related to those found in other canine mycoplasmas, specifically Mycoplasma canis, M. cynos, M. molare and M. maculosa . This is only the second known report of disease caused by M. edwardii in a non-canid species, and the first report of it infecting and causing clinical disease in a cat. |
