The multimodal imaging features and outcomes of multifocal choroiditis/punctate inner choroidopathy lesion with multiple evanescent white dot syndrome-like features: a retrospective study.

Autor: Chen C; Department of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.; Beijing Ophthalmology and Visual Science Key Laboratory, Beijing, China., Cheng Y; Department of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.; Beijing Ophthalmology and Visual Science Key Laboratory, Beijing, China.; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China., Zhang Z; Department of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.; Beijing Ophthalmology and Visual Science Key Laboratory, Beijing, China., Zhang Y; Department of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.; Beijing Ophthalmology and Visual Science Key Laboratory, Beijing, China.; Beijing Institute of Ophthalmology, Beijing, China., Hou S; Department of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.; Beijing Ophthalmology and Visual Science Key Laboratory, Beijing, China., Wang G; Department of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.; Beijing Ophthalmology and Visual Science Key Laboratory, Beijing, China., Peng X; Department of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China. 74000041@ccmu.edu.cn.; Beijing Ophthalmology and Visual Science Key Laboratory, Beijing, China. 74000041@ccmu.edu.cn.
Jazyk: angličtina
Zdroj: BMC ophthalmology [BMC Ophthalmol] 2024 Jan 02; Vol. 24 (1), pp. 3. Date of Electronic Publication: 2024 Jan 02.
DOI: 10.1186/s12886-023-03277-6
Abstrakt: Background: Multiple evanescent white dot syndrome (MEWDS)-like features is a rare condition triggered by a macular disease or iatrogenic injury, exhibiting MEWDS changes in the fundus. This study aims to describe the multimodal imaging features and outcomes of multifocal choroiditis/punctate inner choroidopathy (MFC/PIC) lesions with MEWDS-like features.
Methods: Six cases were studied retrospectively. All cases were given regional and oral corticosteroids.
Results: All cases showed an isolated juxtafoveal yellowish-white MFC/PIC lesion with disruption of RPE-Bruch's membrane-choriocapillaris complex (RPE-BM-CC), subretinal hyperreflective materials and choroidal thickening on optical coherence tomography. Two weeks after presentation, the grayish-white dots disappeared spontaneously and the corticosteroids were given. After four weeks, the ellipsoid zone (EZ) around the lesion and hyper-autofluorescence resolved. After 13 weeks, five cases showed shrinkage of the juxtafoveal lesion and restoration of foveal EZ. After six months, the juxtafoveal lesion became pigmented. Only one case developed type 2 choroidal neovascularization.
Conclusions: The clinical course of MEWDS-like manifestations is still evanescent in our cases. The yellowish-white juxtafoveal MFC/PIC lesions with disruption of RPE-BM-CC and choroidal thickening showed a well-controlled prognosis after corticosteroid treatment.
(© 2024. The Author(s).)
Databáze: MEDLINE
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