Prevalence of co-infection with human papillomavirus and Chlamydia trachomatis and risk factors associated with cervical cancer in Congolese women.

Autor: Ngombe Mouabata DFL; Team of Virology Oncology and Biotechnologies Laboratory of Virology, Oncology, Biosciences, Environment and New Energy, Faculty of Science and Technology, Mohammedia, Hassan II University of Casablanca, Casablanca, Morocco; Department of Health and Human Biology, Faculty of Health Sciences, Marien N'gouabi University, Brazzaville, Congo., Boumba ALM; Department of Health and Human Biology, Faculty of Health Sciences, Marien N'gouabi University, Brazzaville, Congo; Molecular Biology Laboratory of the Polyclinique de la Fondation Marie Madeleine Gombes, Congo; Pointe-Noire Research Zone, National Institute for Research in Health Sciences (IRSSA), Brazzaville, Congo., Massengo NRB; Department of Health and Human Biology, Faculty of Health Sciences, Marien N'gouabi University, Brazzaville, Congo., Pouki FS; Department of Health and Human Biology, Faculty of Health Sciences, Marien N'gouabi University, Brazzaville, Congo., Moukassa D; Department of Health and Human Biology, Faculty of Health Sciences, Marien N'gouabi University, Brazzaville, Congo., Ennaji MM; Team of Virology Oncology and Biotechnologies Laboratory of Virology, Oncology, Biosciences, Environment and New Energy, Faculty of Science and Technology, Mohammedia, Hassan II University of Casablanca, Casablanca, Morocco. Electronic address: m.ennaji@yahoo.fr.
Jazyk: angličtina
Zdroj: Microbes and infection [Microbes Infect] 2024 Mar-Apr; Vol. 26 (3), pp. 105287. Date of Electronic Publication: 2023 Dec 30.
DOI: 10.1016/j.micinf.2023.105287
Abstrakt: The human papillomavirus (HPV) is one of the most frequently diagnosed viruses in developing countries. Chlamydia trachomatis (CT) is an important cofactor in HPV-induced cervical cancer. Cervico-uterine smears were taken for cytology, and a total of 131 samples were analysed. HPV prevalence and CT were detected using specific primers (L1 gene and omp-1 gene). 23 (17.5 %) HPV-only samples were detected, CT-only positives were 10 (7.6 %). And HPV/CT co-infection was 13 (9.9 %). Identified risk factors associated with HPV/CT co-infection were risky sexual behaviour and cytology status. The prevalence of HPV and CT and their co-infection rates being high in our study population, may be an indicator of cervical cancer risk. Consequently, there is an urgent need to raise awareness and take appropriate precautions.
Competing Interests: Declaration of competing interest The authors declare no conflict of interest.
(Copyright © 2023. Published by Elsevier Masson SAS.)
Databáze: MEDLINE
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