Antioxidant Activity of Auricularia auricula Polysaccharides with Different Molecular Weights and Cytotoxicity Difference of Polysaccharides Regulated CaOx to HK-2 Cells.
Autor: | Heng BL; Yingde Center, Institute of Kidney Surgery, Jinan University, Guangzhou, Guangdong, China.; Department of Urology, People's Hospital of Yingde City, Yingde, China., Wu FY; Yingde Center, Institute of Kidney Surgery, Jinan University, Guangzhou, Guangdong, China.; Department of Urology, People's Hospital of Yingde City, Yingde, China., Liu JH; Institute of Biomineralization and Lithiasis Research, Jinan University, Guangzhou 510632, China., Ouyang JM; Institute of Biomineralization and Lithiasis Research, Jinan University, Guangzhou 510632, China. |
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Jazyk: | angličtina |
Zdroj: | Bioinorganic chemistry and applications [Bioinorg Chem Appl] 2023 Dec 23; Vol. 2023, pp. 9968886. Date of Electronic Publication: 2023 Dec 23 (Print Publication: 2023). |
DOI: | 10.1155/2023/9968886 |
Abstrakt: | Objective: This study aimed to investigate the growth of calcium oxalate (CaOx) crystals regulated by Auricularia auricular polysaccharides (AAPs) with different viscosity-average molecular weights ( M Methods: The scavenging capability and reducing capacity of four kinds of AAPs ( M Results: The in vitro antioxidant activities of the four AAPs were observed in the following order: AAP0 < AAP1 < AAP2 < AAP3. Thus, AAP3, which had the smallest M Conclusion: AAPs, particularly AAP3, showed an excellent antioxidative capability in vitro, and AAP3-regulated CaOx crystals presented minimal cytotoxicity. Competing Interests: The authors declare that they have no conflicts of interest. (Copyright © 2023 Bao-Li Heng et al.) |
Databáze: | MEDLINE |
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