The mediation and interaction of the obesity index between moderate-vigorous recreational physical activity and hypertension.

Autor: Du B; School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.; Guangdong Provincial Engineering Research Center of Public Health Detection and Assessment, Guangdong Pharmaceutical University, Guangzhou, China.; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Disease, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China., Li Y; School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.; Guangdong Provincial Engineering Research Center of Public Health Detection and Assessment, Guangdong Pharmaceutical University, Guangzhou, China., Xia Y; School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.; Guangdong Provincial Engineering Research Center of Public Health Detection and Assessment, Guangdong Pharmaceutical University, Guangzhou, China., Wu S; School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.; Guangdong Provincial Engineering Research Center of Public Health Detection and Assessment, Guangdong Pharmaceutical University, Guangzhou, China., Wei Y; School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.; Guangdong Provincial Engineering Research Center of Public Health Detection and Assessment, Guangdong Pharmaceutical University, Guangzhou, China., Wang Z; School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.; Guangdong Provincial Engineering Research Center of Public Health Detection and Assessment, Guangdong Pharmaceutical University, Guangzhou, China., Wang S; School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.; Guangdong Provincial Engineering Research Center of Public Health Detection and Assessment, Guangdong Pharmaceutical University, Guangzhou, China., Guo J; Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine, Guangzhou, China.; Key Laboratory of Glucolipid Metabolic Disorder, Guangzhou, China.; Institute of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China.; Guangdong TCM Key Laboratory for Metabolic Diseases, Guangzhou, China., Zhu Q; Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine, Guangzhou, China.; Key Laboratory of Glucolipid Metabolic Disorder, Guangzhou, China.; Institute of Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou, China., Shen T; School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.; Guangdong Provincial Engineering Research Center of Public Health Detection and Assessment, Guangdong Pharmaceutical University, Guangzhou, China., Chen Q; School of Public Health, Guangdong Pharmaceutical University, Guangzhou, China.; Guangdong Provincial Engineering Research Center of Public Health Detection and Assessment, Guangdong Pharmaceutical University, Guangzhou, China.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2023 Dec 28; Vol. 18 (12), pp. e0296333. Date of Electronic Publication: 2023 Dec 28 (Print Publication: 2023).
DOI: 10.1371/journal.pone.0296333
Abstrakt: Previous studies showed that physical activity (PA) is concerned with hypertension (HTN). However, the mediation and interaction role of the obesity index: body mass index (BMI), waist-hip ratio (WHR), body fat rate (BFR) and visceral fat index (VFI) between PA and HTN has never been studied. Therefore, the purpose of this study was to assess the mediation and interaction of the obesity index between moderate-vigorous recreational physical activity (MVRPA) and HTN. We conducted a cross-sectional study of 4710 individuals aged 41 or older in Torch Development Zone, Zhongshan City. The mediation and interaction of the obesity index were evaluated by a four-way decomposition. 48.07% of participants had HTN among these groups. In the adjusted linear regression model, MVRPA was significantly correlated with WHR (β±SE = -0.005±0.002; P<0.05). Compared to sufficient MVRPA (odds ratio (OR) = 1.35), 95% (confidence interval (CI) = 1.17-1.56), insufficient MVRPA increased the risk of developing HTN. Furthermore, there were associations between BMI, WHR, BFR, VFI and HTN where the adjusted ORs and 95% CIs were 1.11 (1.09-1.13), 6.23 (2.61-14.90), 1.04 (1.03-1.06), 1.07 (1.06-1.09), respectively. The mediation analyses suggested that the impact of MVRPA on HTN risk may partly be explained by changes in obesity index, with a pure indirect mediation of WHR between MVRPA and HTN (P<0.05). Therefore, weight control, especially reducing abdominal obesity and maintaining adequate MVRPA, may lead to more proper control of HTN.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright: © 2023 Du et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje