Neonatal Outcomes of Critical Congenital Heart Defects: A Multicenter Epidemiological Study of Turkish Neonatal Society : Neonatal Outcomes of CCHD.

Autor: Dilli D; Department of Neonatology, Dr. Sami Ulus Research and Application Center, Health Science University of Turkey, Ankara, Turkey. dilekdilli2@yahoo.com., Akduman H; Department of Neonatology, Dr. Sami Ulus Research and Application Center, Health Science University of Turkey, Ankara, Turkey., Zenciroğlu A; Department of Neonatology, Dr. Sami Ulus Research and Application Center, Health Science University of Turkey, Ankara, Turkey., Çetinkaya M; Department of Neonatology, Başakşehir Çam Sakura City Hospital, Health Science University of Turkey, İstanbul, Turkey., Okur N; Department of Neonatology, Gazi Yaşargil Research and Application Center, Health Science University of Turkey, Diyarbakır, Turkey., Turan Ö; Department of Neonatology, Başkent University, Medical Faculty, Ankara, Turkey., Özlü F; Department of Neonatology, Çukurova University, Medical Faculty, Adana, Turkey., Çalkavur Ş; Department of Neonatology, Dr. Behçet Uz Pediatric Diseases and Surgery Training and Research Hospital, Health Science University of Turkey, İzmir, Turkey., Demirel G; Department of Neonatology, İstanbul Medipol University, International Faculty of Medicine, Istanbul, Turkey., Koksal N; Department of Neonatology, Uludağ University, Medical Faculty, Bursa, Turkey., Çolak R; Department of Neonatology, Beykent University Medical Faculty, Istanbul, Turkey., Örün UA; Department of Pediatric Cardiology, Dr. Sami Ulus Research and Application Center, Health Science University of Turkey, Ankara, Turkey., Öztürk E; Department of Pediatric Cardiology, Başakşehir Çam Sakura City Hospital, Health Science University of Turkey, Istanbul, Turkey., Gül Ö; Department of Pediatric Cardiology, Gazi Yaşargil Research and Application Center, Health Science University of Turkey, Diyarbakır, Turkey., Tokel NK; Department of Pediatric Cardiology, Başkent University, Medical Faculty, Ankara, Turkey., Erdem S; Department of Pediatric Cardiology, Çukurova University, Medical Faculty, Adana, Turkey., Meşe T; Department of Pediatric Cardiology, Dr. Behçet Uz Pediatric Diseases and Surgery Training and Research Hospital, Health Science University of Turkey, İzmir, Turkey., Erdem A; Department of Pediatric Cardiology, İstanbul Medipol University, International Faculty of Medicine, İstanbul, Turkey., Bostan ÖM; Department of Pediatric Cardiology, Uludağ University, Medical Faculty, Bursa, Turkey., Polat TB; Department of Pediatric Cardiology, Beykent University, Medical Faculty, İstanbul, Turkey., Taşar M; Department of Pediatric Cardiovascular Surgery, Dr. Sami Ulus Research and Application Center, Health Science University of Turkey, Ankara, Turkey., Hatemi AC; Department of Pediatric Cardiovascular Surgery, Başakşehir Çam Sakura City Hospital, Health Science University of Turkey, İstanbul, Turkey., Doyurgan O; Department of Pediatric Cardiovascular Surgery, Gazi Yaşargil Research and Application Center, Health Science University of Turkey, Diyarbakır, Turkey., Özkan M; Department of Pediatric Cardiovascular Surgery, Başkent University, Medical Faculty, Ankara, Turkey., Avşar MK; Department of Pediatric Cardiovascular Surgery, Çukurova University, Medical Faculty, Adana, Turkey., Sarıosmanoğlu ON; Department of Pediatric Cardiovascular Surgery, Dr. Behçet Uz Pediatric Diseases and Surgery Training and Research Hospital, Health Science University of Turkey, İzmir, Turkey., Uğurlucan M; Department of Pediatric Cardiovascular Surgery, İstanbul Medipol University, International Faculty of Medicine, İstanbul, Turkey., Sığnak IŞ; Department of Pediatric Cardiovascular Surgery, Uludağ University, Medical Faculty, Bursa, Turkey., Başaran M; Department of Pediatric Cardiovascular Surgery, Beykent University, Medical Faculty, Istanbul, Turkey.
Jazyk: angličtina
Zdroj: Pediatric cardiology [Pediatr Cardiol] 2024 Feb; Vol. 45 (2), pp. 257-271. Date of Electronic Publication: 2023 Dec 28.
DOI: 10.1007/s00246-023-03362-z
Abstrakt: Critical congenital heart disease (CCHD) is one of the leading causes of neonatal and infant mortality. We aimed to elucidate the epidemiology, spectrum, and outcome of neonatal CCHD in Türkiye. This was a multicenter epidemiological study of neonates with CCHD conducted from October 2021 to November 2022 at national tertiary health centers. Data from 488 neonatal CCHD patients from nine centers were entered into the Trials-Network online registry system during the study period. Transposition of great arteria was the most common neonatal CHD, accounting for 19.5% of all cases. Sixty-three (12.9%) patients had extra-cardiac congenital anomalies. A total of 325 patients underwent cardiac surgery. Aortic arch repair (29.5%), arterial switch (25.5%), and modified Blalock-Taussig shunt (13.2%). Overall, in-hospital mortality was 20.1% with postoperative mortality of 19.6%. Multivariate analysis showed that the need of prostaglandin E1 before intervention, higher VIS (> 17.5), the presence of major postoperative complications, and the need for early postoperative extracorporeal membrane oxygenation were the main risk factors for mortality. The mortality rate of CCHD in our country remains high, although it varies by health center. Further research needs to be conducted to determine long-term outcomes for this vulnerable population.
(© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
Databáze: MEDLINE
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